Results 31 to 40 of about 1,429 (148)

Tetrazine Ligation in Living Systems: Beyond Fast Kinetics to Effective Bioorthogonality

Chemistry – A European Journal, EarlyView.
Rapid reaction kinetics (k2) alone do not ensure successful tetrazine ligation in living systems. This review introduces ‘effective orthogonality’—focusing on chemical survival, availability, and encounter—as a practical framework. We highlight how bottlenecks shift from cellular sinks to in vivo delivery limits, offering design strategies for reliable
Junhyeong Yim, Junyoung Park, Youngjun Lee, Jongmin Park   +3 more
wiley   +1 more source

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

Chemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato, Philipp Natho, Marco Colella, Renzo Luisi   +3 more
wiley   +1 more source

Anode/Electrolyte Interfacial Engineering Toward Sustainable and Practical Solid‐State Metal‐Sulfur Batteries: A Prospective Review

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Coordinated engineering of the anode, electrolyte, and interface underpins the rational design of next‐generation solid‐state metal‐sulfur batteries. Solid‐state metal‐sulfur batteries are emerging as a transformative energy storage platform with the potential to overcome the fundamental limitations of conventional flooded cells, particularly ...
Ziyu Feng, Hong Zhang, Peng Wang, Ke Lu, Fei Du   +4 more
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

Exploration, EarlyView.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang, Shuai Tian, Qinyu Han, Yulin Deng, Jiatao Zhang, Enqiang Linghu, Qianqian Chen, Zhimin Wang   +7 more
wiley   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Multi‐Responsive PAA/PNIPAM Semi‐IPN Hydrogel Properties Controlled by PAA Topology

Macromolecular Rapid Communications, EarlyView.
Polymer topology governs hydrogel behavior in semi‐interpenetrating networks. Cyclic poly(acrylic acid) enables controlled pH‐responsive swelling, improved stability, and enhanced deformability compared to linear analogues, while linear systems show higher strength during thermal de‐swelling.
Suraj Aswale, Gyeong Min Choi, Hyerin Kang, Aruna Kumar Mohanty, Hanyoung Kim, Hong Y. Cho, Heon Sang Lee, Hyun‐jong Paik   +7 more
wiley   +1 more source

Diverse reactivity of maleimides in polymer science and beyond

Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick, Kristi S Anseth, Tayler S Hebner   +2 more
wiley   +1 more source

Main‐chain polyfullerenes: Taking fullerene to the next dimension

Polymer International, EarlyView.
This short review appraises main‐chain polyfullerenes. Their slow development over 30 years has suddenly boomed with a rapid growth due to exciting developments in solar energy. Abstract This mini‐review gives an overview of the development, chemistry, properties and applications of main‐chain polyfullerenes.
Marco Antônio GB Gomes, Orisson Ponce Gomes, Patricia Targon Campana, Didier Bégué, Roger C Hiorns   +4 more
wiley   +1 more source

Purification and Properties of Polyvinyl Nitrate and Its Compatibility With Solid Oxidizers

Propellants, Explosives, Pyrotechnics, EarlyView.
ABSTRACT Polyvinyl nitrate (PVN) is a nitrate‐ester energetic binder that can be produced directly from polyvinyl alcohol—a cheap commodity feedstock—thereby offering potential cost and supply‐chain advantages over binders based on nitrocellulose and other specialty polymers.
Stephen Spice, Monica C. Chandwani, Carole A. Morrison, Colin R. Pulham   +3 more
wiley   +1 more source