Results 11 to 20 of about 1,429 (148)
Synthetic Strategies for Activity-Based Probes to Decode Ubiquitin-Like Modifiers. [PDF]
ChemistryABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Chanda S +5 more
europepmc +2 more sources
Frontiers in Chemistry, 2022 A chemodivergent photocatalytic approach to 1-pyrrolines and 1-tetralones from alkyl bromides and vinyl azides has been developed through chemoselectively controllable intermolecular [3 + 2] and [4 + 2] cyclization.
Shijing Tu +9 more
doaj +1 more source
CHIMIA, 2012 Mn(iii)-catalyzed formal [3+2]- and [3+3]-annulations have been developed using readily available vinyl azides with 1,3-dicarbonyl compounds and cyclopropanols.
Shunsuke Chiba
doaj +1 more source
Bortrifluorid-katalysierte Umsetzung von 2H-Azirinen und Vinylaziden mit Nitrilen
CHIMIA, 1975 The reaction of 2H-azirines or vinyl azides with nitriles in the presence of boron trifluoride etherate, to yield the corresponding imidazoles (see table), is described.
Heinz Bader, Hans-Jürgen Hansen
doaj +1 more source
Copper-Catalyzed Amination of Vinyl Azides to α-Ketoamides
SynOpen, 2019 An efficient approach for the amination of vinyl azides with N,N-dialkylacylamides has been developed. By using this protocol, structurally important α-ketoamides can be easily synthesized.
Yu Wang +6 more
doaj +1 more source
Continuous multistep synthesis of 2-(azidomethyl)oxazoles
Beilstein Journal of Organic Chemistry, 2018 An efficient three-step protocol was developed to produce 2-(azidomethyl)oxazoles from vinyl azides in a continuous-flow process. The general synthetic strategy involves a thermolysis of vinyl azides to generate azirines, which react with bromoacetyl ...
Thaís A. Rossa +4 more
doaj +1 more source
Expeditious diastereoselective synthesis of elaborated ketones via remote Csp3–H functionalization
Nature Communications, 2017 C-H activation is a powerful method to form functionalised molecules, but is particularly challenging for unactivated sp3sites. Here the authors report a directing-group-free radical cascade process for converting vinyl azides and carboxylic acids to ...
Wei Shu +3 more
doaj +1 more source
Green Chemistry Letters and Reviews, 2018 An efficient and ecofriendly method for the synthesis of disubstituted 5-aminopyrimidines from vinyl azides and urea or thiourea was developed. This reaction proceeds under microwave irradiation conditions in the presence of water as a solvent.
Oussama Dehbi +8 more
doaj +1 more source
Conversions of sulfone-containing vinyl azides to vinyl triazoles and enamides
Tetrahedron, 2021 Abstract- Reported is the efficient conversion of four 3-sulfonyl prop-1-enyl azides into seven 3-sulfonyl prop-1-enyl triazoles. Results demonstrate that the stereochemical integrity of the alkene was maintained during this process. The conversion of (Z)-((3-azidoallyl)sulfonyl)benzene into the corresponding Z-enamides proved more challenging and ...
Niall Collins +2 more
openaire +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source