Results 41 to 50 of about 235,748 (267)

Changes in firearm intentions and behaviors after the 2024 United States presidential election

Injury Epidemiology
Background Firearm purchasing patterns, intentions, and behaviors change over time in response to specific events. Additionally, the nature of these changes may be evolving over time or differ depending on the nature of the event in question.
Michael D. Anestis, Allison E. Bond, Kimberly C. Burke, Sultan Altikriti, Daniel C. Semenza   +4 more
doaj   +1 more source

The relationship between posttraumatic stress symptoms and narrative structure among adolescent terrorist-attack survivors

European Journal of Psychotraumatology, 2016
Background: The structure of trauma narratives is considered to be related to posttraumatic stress symptomatology and thus the capacity to make a coherent narrative after stressful events is crucial for mental health.
Petra Filkuková, Tine K. Jensen, Gertrud Sofie Hafstad, Hanne Torvund Minde, Grete Dyb   +4 more
doaj   +1 more source

Is perceived safety and threat after workplace terrorism linked to employee sick-leave? A registry-based longitudinal study of governmental employees in Norway

European Journal of Psychotraumatology, 2020
Background A large body of research has shown that terrorism enhances fears and undermines perceived safety in a high proportion of both directly exposed individuals and individuals without any form of direct exposure (i.e.
Alexander Nissen, Mona Berthelsen, Maria Teresa Grønning Dale, Marianne Bang Hansen, Trond Heir   +4 more
doaj   +1 more source

Association of medical conditions and firearm suicide among legal handgun purchasers in California: a case–control study

Injury Epidemiology, 2023
Background Suicide is a pressing public health problem, and firearm owners are at especially elevated risk. Certain health conditions are markers of suicide risk, but more research is needed on clinical risk markers for suicide among firearm owners ...
Julia P. Schleimer, Rose M. C. Kagawa, Hannah S. Laqueur   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Police Views of Suicidal Persons and the Law Criminalizing Attempted Suicide in Ghana: A Qualitative Study With Policy Implications

SAGE Open, 2017
The penal code of Ghana condemns suicide attempt. The present study sought to explore the views of the police on persons who attempt suicide and the law criminalizing the act.
Joseph Osafo, Charity S. Akotia, Emmanuel N.-B. Quarshie, Kofi E. Boakye, Johnny Andoh-Arthur   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Political affiliation moderates the link between gun violence exposure and firearm behaviors via perceptions of utility, safety, and threat

Injury Epidemiology
Background Gun violence exposure (GVE) is associated with a range of cognitive and behavioral outcomes. However, few studies have assessed how different forms of GVE relate to perceptions of safety, threat sensitivity, and views about the utility of ...
Sultan Altikriti, Daniel C. Semenza, Michael D. Anestis   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source