Results 81 to 90 of about 273,852 (324)
Zhongguo cuzhong zazhi, 2018 重要性 跌倒是美国老年人群中首位伤害相关的致残和致死原因。2014年，28.7%社区65岁及以上 老年人经历过跌倒，导致2015年2900万次跌倒（37.5%需要药物治疗或1 d及以上的限制活动），估计 有3.3万人死亡。 目的 更新2012年美国预防服务工作组（US Preventive Services Task Force，USPSTF）针对社区老年人 跌倒预防措施的推荐意见。 证据回顾 USPSTF回顾了针对无骨质疏松及维生素D缺乏的社区65岁及以上老年人群预防跌倒及跌 ...
译者：李金鑫，李宁，高婷，刘丽君，鞠奕，赵性泉
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An objective structural and functional reference standard in glaucoma
Scientific Reports, 2021 The current lack of consensus for diagnosing glaucoma makes it difficult to develop diagnostic tests derived from deep learning (DL) algorithms. In the present study, we propose an objective definition of glaucomatous optic neuropathy (GON) using clearly
Eduardo B. Mariottoni +5 more
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, 2015 In order to design clusters with desired properties, we have implemented a suite of genetic algorithms tailored to optimize for low total energy, high vertical electron affinity (VEA), and low vertical ionization potential (VIP). Applied to (TiO$_2$)$_n$
Bhattacharya, Saswata +4 more
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Vasoactive Intestinal Peptide maintains the non-pathogenic profile of human Th17-polarized cells [PDF]
, 2014 The cytokine microenvironment modulates CD4 T cell differentiation causing the shift of naïve CD4 T cells into different cell subsets. This process is also regulated by modulators such as VIP, a neuropeptide with known immunomodulatory properties on CD4 ...
Carrión Caballo, Mar +9 more
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Cerebral Cortex, 2015 Neocortical GABAergic interneurons have a profound impact on cortical circuitry and its information processing capacity. Distinct subgroups of inhibitory interneurons can be distinguished by molecular markers, such as parvalbumin, somatostatin, and ...
Alvar Prönneke +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Advanced Science, EarlyView.TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen +16 more
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Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
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Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Hepatology, EarlyView., 2022 Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source
VIP: Finding Important People in Images
, 2015 People preserve memories of events such as birthdays, weddings, or vacations by capturing photos, often depicting groups of people. Invariably, some individuals in the image are more important than others given the context of the event.
Batra, Dhruv +2 more
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