Assessing the Utility of Broad-Acting Inhibitors as Therapeutics in Diverse Venoms [PDF]
ToxinsExamination of venom constituent bioactivities from diverse venomous animals shows certain highly conserved classes, including enzymes (e.g., phospholipases and metalloproteinases) and pore-forming proteins.
Raechel Kadler +2 more
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Commercial Antivenoms Exert Broad Paraspecific Immunological Binding and In Vitro Inhibition of Medically Important Bothrops Pit Viper Venoms. [PDF]
Toxins (Basel), 2022 Alsolaiss J +3 more
europepmc +3 more sources
Differential effects of the venoms of Russell’s viper and Indian cobra on human myoblasts [PDF]
Scientific ReportsLocal tissue damage following snakebite envenoming remains a poorly researched area. To develop better strategies to treat snakebites, it is critical to understand the mechanisms through which venom toxins induce envenomation effects including local ...
Husain Bin Haidar +7 more
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Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell’s viper (Daboia russelii) venoms [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background: The western Russell’s viper (Daboia russelii) is widely distributed in South Asia, and geographical venom variation is anticipated among distant populations.
Tasnim Faisal +5 more
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From birth to bite: the evolutionary ecology of India's medically most important snake venoms [PDF]
BMC BiologyBackground Snake venoms can exhibit remarkable inter- and intraspecific variation. While diverse ecological and environmental factors are theorised to explain this variation, only a handful of studies have attempted to unravel their precise roles.
R. R. Senji Laxme +4 more
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Toxins, 2023 Snakebite envenoming is a neglected tropical disease prevalent in South Asia. In Pakistan, antivenoms are commonly imported from India despite the controversy over their effectiveness.
Andy Shing Seng Lim +6 more
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Survival intravascular photoacoustic imaging of lipid‐rich plaque in cholesterol fed rabbits
Translational Biophotonics, Volume 4, Issue 4, December 2022., 2022 Early identification of vulnerable plaques in vivo can have a positive impact on guiding the treatment of cardiovascular disease. In this work, Ji‐Xin Cheng and coworkers demonstrate survival intravascular photoacoustic imaging of lipid‐laden plaques in live cholesterol‐fed rabbits.
Yi Zhang +4 more
wiley +1 more source
Effective equine immunization protocol for production of potent poly-specific antisera against Calloselasma rhodostoma, Cryptelytrops albolabris and Daboia siamensis. [PDF]
PLoS Neglected Tropical Diseases, 2015 Snake envenomation has been estimated to affect 1.8 million people annually with about 94,000 deaths mostly in poor tropical countries. Specific antivenoms are the only rational and effective therapy for these cases.
Sompong Sapsutthipas +5 more
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Wildlife Biology, EarlyView., 2023 The Hungarian meadow viper is an endangered grassland‐dwelling species, which faces high predation pressure, partially due to avian species that forage in its habitat. Predation pressure by avian predators is caused not only by abundant game species (e.g. hooded crow, Corvus cornix) but also by protected and threatened species (e.g.
Edvárd Mizsei +11 more
wiley +1 more source
Toxins, 2020 Snake venoms contain components selected to immobilize prey. The venoms from Elapidae mainly contain neurotoxins, which are critical for rapid prey paralysis, while the venoms from Viperidae and Colubridae may contain fewer neurotoxins but are likely to ...
Huiwen Tian +9 more
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