Results 11 to 20 of about 63,532 (247)

Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell’s viper (Daboia russelii) venoms [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2021
Background: The western Russell’s viper (Daboia russelii) is widely distributed in South Asia, and geographical venom variation is anticipated among distant populations.
Tasnim Faisal, Kae Yi Tan, Nget Hong Tan, Si Mui Sim, Christeine Ariaranee Gnanathasan, Choo Hock Tan   +5 more
doaj   +2 more sources

Bite First, Bleed Later: How Philippine Trimeresurus Pit Viper Venoms Hijack Blood Clotting [PDF]

Toxins
The Philippines has a high diversity of venomous snake species, but there is minimal information on their envenomation effects. This is evidenced by the small number of case reports, the poor reporting of envenomation cases, and the absence of specific ...
Daniel Albert E. Castillo, Lorenzo Seneci, Abhinandan Chowdhury, Marilyn G. Rimando, Bryan G. Fry   +4 more
doaj   +2 more sources

Differential Effects of Marimastat and Prinomastat on the Metalloprotease Activity of Various Snake Venoms [PDF]

Toxins
Snakebite envenoming is a neglected tropical disease, responsible for approximately 140,000 deaths globally each year. Vipers and elapid snakes represent the most significant snake families in medical contexts, exhibiting a variety of venom components ...
Mahtab Khatibi, José R. Almeida, Soheil Gilabadi, David Ramírez, Paulina Valenzuela-Hormazábal, Ketan Patel, Sakthivel Vaiyapuri   +6 more
doaj   +2 more sources

Proteomic Analysis, Immuno-Specificity and Neutralization Efficacy of Pakistani Viper Antivenom (PVAV), a Bivalent Anti-Viperid Antivenom Produced in Pakistan

Toxins, 2023
Snakebite envenoming is a neglected tropical disease prevalent in South Asia. In Pakistan, antivenoms are commonly imported from India despite the controversy over their effectiveness.
Andy Shing Seng Lim, Kae Yi Tan, Naeem H. Quraishi, Saud Farooque, Zahoor Ahmed Khoso, Kavi Ratanabanangkoon, Choo Hock Tan   +6 more
doaj   +2 more sources

The Clotting Action of Russell Viper Venom [PDF]

Blood, 1954
Abstract 1. It has been shown that Russell viper venom in the presence of lipoid cofactor can clot hemophilia A plasma, hemophilia B plasma and proconvertin deficient plasma within 5 seconds. It is unable to clot proaccelerin deficient plasma rapidly. Thus the clotting behavior of venom-lipoid is similar to convertin. 2. A
Samuel I. Rapaport, Knut Aas, P. A. Owren   +2 more
openalex   +3 more sources

Differential effects of the venoms of Russell’s viper and Indian cobra on human myoblasts

Scientific Reports
Local tissue damage following snakebite envenoming remains a poorly researched area. To develop better strategies to treat snakebites, it is critical to understand the mechanisms through which venom toxins induce envenomation effects including local ...
Husain Bin Haidar, José R. Almeida, Jarred Williams, Bokai Guo, Anne Bigot, Subramanian Senthilkumaran, Sakthivel Vaiyapuri, Ketan Patel   +7 more
doaj   +2 more sources

Immunological cross-reactivity and neutralisation of European viper venoms with the monospecific Vipera berus antivenom ViperaTAb. [PDF]

Toxins (Basel), 2014
Medically important cases of snakebite in Europe are predominately caused by European vipers of the genus Vipera. The mainstay of snakebite therapy is polyclonal antibody therapy, referred to as antivenom.
Casewell NR, Al-Abdulla I, Smith D, Coxon R, Landon J.   +4 more
europepmc   +2 more sources

Proteomics and antivenom immunoprofiling of Russell’s viper (Daboia siamensis) venoms from Thailand and Indonesia [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background The Eastern Russell’s viper, Daboia siamensis, is a WHO Category 1 medically important venomous snake. It has a wide but disjunct distribution in Southeast Asia. The specific antivenom, D.
Thava Malar Changra Lingam, Kae Yi Tan, Choo Hock Tan   +2 more
doaj   +2 more sources

The Contribution of Phospholipase A₂ and Metalloproteinases to the Synergistic Action of Viper Venom on the Bioenergetic Profile of Vero Cells

Toxins, 2022
Increasing concern about the use of animal models has stimulated the development of in vitro cell culture models for analysis of the biological effects of snake venoms.
Naira Ayvazyan, Gevorg Ghukasyan, Lusine Ghulikyan, Gayane Kirakosyan, Gohar Sevoyan, Armen Voskanyan, Zaruhi Karabekyan   +6 more
doaj   +2 more sources

A comparative cross-reactivity and paraspecific neutralization study on Hypnale hypnale, Echis carinatus, and Daboia russelii monovalent and therapeutic polyvalent anti-venoms.

PLoS Neglected Tropical Diseases, 2022
Envenoming by the hump-nosed pit viper (Hypnale hypnale) raises concern as it inflicts significant debilitation and death in the Western Ghats of India and in the adjacent island nation of Sri Lanka.
Vaddaragudisalu D Sandesha, Bhaskar Darshan, Chandrashekar Tejas, Kesturu S Girish, Kemparaju Kempaiah   +4 more
doaj   +2 more sources