Results 31 to 40 of about 63,532 (247)

Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation

open access: yesFrontiers in Immunology, 2019
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and prominent local inflammation. To date, the mechanisms underlying inflammation and blood coagulation induced by Viperidae venoms have been viewed as distinct processes ...
Catarina Teixeira   +7 more
doaj   +1 more source

Children and Snakebite: Snake Venom Effects on Adult and Paediatric Plasma

open access: yesToxins, 2023
Snakebite is a globally neglected tropical disease, with coagulation disturbances being the primary pathology of many deadly snake venoms. Age-related differences in human plasma have been abundantly reported, yet the effect that these differences pose ...
Christina N. Zdenek   +5 more
doaj   +1 more source

Viper venom for diabetic nephropathy [PDF]

open access: yesKidney International, 2012
Diabetic nephropathy is the leading cause of end-stage renal disease in the United States. Renin-angiotensin-aldosterone system (RAAS) blockers are thought to have a specific renoprotective effect in diabetes. Hirst et al. report the results of randomized clinical trials assessing the effects of RAAS inhibitors on urinary albumin excretion levels in ...
openaire   +2 more sources

Quantitative Proteomic Analysis of Venoms from Russian Vipers of Pelias Group: Phospholipases A2 are the Main Venom Components

open access: yesToxins, 2016
Venoms of most Russian viper species are poorly characterized. Here, by quantitative chromato-mass-spectrometry, we analyzed protein and peptide compositions of venoms from four Vipera species (V. kaznakovi, V. renardi, V. orlovi and V.
Sergey I. Kovalchuk   +4 more
doaj   +1 more source

Evaluation of the Lethal Potency of Scorpion and Snake Venoms and Comparison between Intraperitoneal and Intravenous Injection Routes

open access: yesToxins, 2014
Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Naoual Oukkache   +6 more
doaj   +1 more source

Platelet Desialylation Is a Novel Mechanism and Therapeutic Target in Daboia siamensis and Agkistrodon halys Envenomation-Induced Thrombocytopenia

open access: yesMolecules, 2022
Venom-induced thrombocytopenia (VIT) is one of the most important hemotoxic effects of a snakebite, which is often associated with venom-induced consumptive coagulopathy (VICC).
Cheng Zhang   +8 more
doaj   +1 more source

Venom proteomic analysis of medically important Nigerian viper Echis ocellatus and Bitis arietans snake species

open access: yesBiochemistry and Biophysics Reports, 2021
Snakebite envenoming remains a neglected tropical disease which poses severe health hazard, especially for the rural inhabitants in Africa. In Nigeria, vipers are responsible for the highest number of deaths. Hydrophilic interaction liquid chromatography
Emeka John Dingwoke   +6 more
doaj   +1 more source

Viper Venom Disintegrins and Related Molecules

open access: yesExperimental Biology and Medicine, 1998
The term "disintegrin" was first used in 1990 to describe a group of viper venom-derived, nonenzymatic small proteins that shared numerous structural and functional properties. These proteins, which have been found in a great number of viper species studied since that time possess both a remarkable sequence homology and an equally notable variability ...
M A, McLane   +4 more
openaire   +2 more sources

Potential Role of Platelet-Activating C-Type Lectin-Like Proteins in Viper Envenomation Induced Thrombotic Microangiopathy Symptom

open access: yesToxins, 2020
Envenomation by viperid snakes may lead to severe bleeding, consumption coagulopathy, and thrombotic microangiopathy symptoms. The exact etiology or toxins responsible for thrombotic microangiopathy symptoms after snake envenomation remain obscure. Snake
Chengbo Long   +9 more
doaj   +1 more source

Comparative venom toxin analyses of Nigerian viperidae and elapidae snakes

open access: yesScientific African, 2023
Envenoming by snakebite is a serious health problem that maims and kills a large number of people, primarily in rural areas of developing African countries. The first comparative venom proteomic analyses of four snakes from the viperidae (E.
Fatima Amin Adamude   +5 more
doaj   +1 more source

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