Results 21 to 30 of about 1,330,033 (311)

Complete genome analysis of hepatitis B virus in Qinghai-Tibet plateau: the geographical distribution, genetic diversity, and co-existence of HBsAg and anti-HBs antibodies

open access: yesVirology Journal, 2020
Background The genetic variation and origin of Hepatitis B Virus (HBV) in Qinghai-Tibet Plateau were poorly studied. The coexistence of HBsAg and anti-HBs has been described as a puzzle and has never been reported in the indigenous population or in ...
He Liu   +9 more
doaj   +1 more source

Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1

open access: yesVirology Journal, 2022
Background Nuclear factor E2-related factor 2 (Nrf2) is an important transcription factor which plays a pivotal role in detoxifying reactive oxygen species (ROS) and has been more recently shown to regulate inflammatory and antiviral responses.
Li Zhang   +5 more
doaj   +1 more source

Genetic characteristics of HA gene of influenza A (H1N1) virus isolated from severe and fatal infection cases in Guizhou province in 2019

open access: yesZhongguo gonggong weisheng, 2023
ObjectiveTo analyze characteristics and specific molecular sites of hemagglutinin (HA) gene of influenza A (H1N1) virus isolated among severe and deadly infection cases in Guizhou province in 2019 for providing evidence to influenza prevention and ...
Lijuan REN   +4 more
doaj   +1 more source

Applicability of duplex real time and lateral flow strip reverse-transcription recombinase aided amplification assays for the detection of Enterovirus 71 and Coxsackievirus A16

open access: yesVirology Journal, 2019
Background Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the two main etiological agents of Hand, Foot and Mouth Disease (HFMD). Simple and rapid detection of EV71 and CA16 is critical in resource-limited settings.
Xin-na Li   +11 more
doaj   +1 more source

Restriction-Assembly: A Solution to Construct Novel Adenovirus Vector

open access: yesViruses, 2022
Gene therapy and vaccine development need more novel adenovirus vectors. Here, we attempt to provide strategies to construct adenovirus vectors based on restriction-assembly for researchers with little experience in this field.
Xiaojuan Guo   +7 more
doaj   +1 more source

Vaccination reduces the viral load and the risk of transmission of Jembrana disease virus in Bali cattle

open access: yes, 2009
The efficacy of a tissue-derived vaccine, which is currently used in Indonesia to control the spread of Jembrana disease in Bali cattle, was determined by quantifying the viral load in plasma following experimental infection with Jembrana disease virus ...
Wilcox, G.E.   +11 more
core   +1 more source

Alvira : comparative genomics of viral strains [PDF]

open access: yes, 2007
The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large ...
Fremez, Romain   +7 more
core   +1 more source

Isolation and characterization of WUPyV in polarized human airway epithelial cells

open access: yesBMC Infectious Diseases, 2020
Background Washington University polyomavirus (WUPyV) is a novel human polyomavirus detected in childwith acute respiratory infection in 2007. However, the relationship between WUPyV and respiratory diseases has yet to be established for lacking of a ...
Chao Wang   +7 more
doaj   +1 more source

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus

open access: yes, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H.   +7 more
core   +1 more source

Observing micro-evolutionary processes of viral populations at multiple scales [PDF]

open access: yes, 2013
Advances in sequencing technology coupled with new integrative approaches to data analysis provide a potentially transformative opportunity to use pathogen genome data to advance our understanding of transmission.
Orton, Richard J.   +19 more
core   +1 more source

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