Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons. [PDF]
Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and ...
Boback, Scott M +9 more
core +1 more source
Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora +22 more
core +1 more source
Viral-induced neurodegenerative disease. [PDF]
Viral etiology has been postulated in a variety of neurological diseases in humans, including multiple sclerosis. Several experimental animal models of viral-induced neurodegenerative disease provide insight into potential host- and pathogen-dependent ...
Buchmeier, MJ, Lane, TE
core +1 more source
A minimal stochastic model for influenza evolution
We introduce and discuss a minimal individual-based model for influenza dynamics. The model takes into account the effects of specific immunization against viral strains, but also infectivity randomness and the presence of a short-lived strain ...
Drake J W +8 more
core +1 more source
454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology [PDF]
Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies.
Ackermann +13 more
core +3 more sources
Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan +3 more
core +2 more sources
The interplay between viral-derived miRNAs and host immunity during infection [PDF]
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad +3 more
core +1 more source
Effect of dsRNA on Mesangial Cell Synthesis of Plasminogen Activator Inhibitor Type 1 and Tissue Plasminogen Activator [PDF]
Background/Aims: Viral infections are a major problem worldwide and many of them are complicated by virally induced glomerulonephritides. Progression of kidney disease to renal failure is mainly attributed to the development of renal fibrosis ...
Merkle, Monika +4 more
core +1 more source
The causes and consequences of seasonal variation in COPD exacerbations [PDF]
Gavin C Donaldson, Jadwiga A Wedzicha Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK Abstract: The time of year when patients experience exacerbations of chronic obstructive pulmonary disease is a much ...
Donaldson, G, Wedzicha, J
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Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study. [PDF]
BackgroundThe capacity of electronic health record (EHR) data to guide targeted surveillance in chronic kidney disease (CKD) is unclear. We sought to leverage EHR data for predicting risk of progressing from CKD to end-stage renal disease (ESRD) to help ...
Chertow, Glenn M +5 more
core +2 more sources

