Results 21 to 30 of about 6,506,858 (262)

Complete genome analysis of hepatitis B virus in Qinghai-Tibet plateau: the geographical distribution, genetic diversity, and co-existence of HBsAg and anti-HBs antibodies

open access: yesVirology Journal, 2020
Background The genetic variation and origin of Hepatitis B Virus (HBV) in Qinghai-Tibet Plateau were poorly studied. The coexistence of HBsAg and anti-HBs has been described as a puzzle and has never been reported in the indigenous population or in ...
He Liu   +9 more
doaj   +1 more source

Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1

open access: yesVirology Journal, 2022
Background Nuclear factor E2-related factor 2 (Nrf2) is an important transcription factor which plays a pivotal role in detoxifying reactive oxygen species (ROS) and has been more recently shown to regulate inflammatory and antiviral responses.
Li Zhang   +5 more
doaj   +1 more source

Genetic characteristics of HA gene of influenza A (H1N1) virus isolated from severe and fatal infection cases in Guizhou province in 2019

open access: yesZhongguo gonggong weisheng, 2023
ObjectiveTo analyze characteristics and specific molecular sites of hemagglutinin (HA) gene of influenza A (H1N1) virus isolated among severe and deadly infection cases in Guizhou province in 2019 for providing evidence to influenza prevention and ...
Lijuan REN   +4 more
doaj   +1 more source

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

open access: yes, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J   +59 more
core   +1 more source

Applicability of duplex real time and lateral flow strip reverse-transcription recombinase aided amplification assays for the detection of Enterovirus 71 and Coxsackievirus A16

open access: yesVirology Journal, 2019
Background Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the two main etiological agents of Hand, Foot and Mouth Disease (HFMD). Simple and rapid detection of EV71 and CA16 is critical in resource-limited settings.
Xin-na Li   +11 more
doaj   +1 more source

Restriction-Assembly: A Solution to Construct Novel Adenovirus Vector

open access: yesViruses, 2022
Gene therapy and vaccine development need more novel adenovirus vectors. Here, we attempt to provide strategies to construct adenovirus vectors based on restriction-assembly for researchers with little experience in this field.
Xiaojuan Guo   +7 more
doaj   +1 more source

Applications of viral metagenomics in the veterinary field [PDF]

open access: yes, 2010
Viral metagenomics provide a powerful technology to investigate the viral flora of healthy and sick animals. Using these methodologies, we gain a better understanding in the etiology of diseases, as well as deepen our knowledge into the viruses ...
Blomström, Anne-Lie
core   +1 more source

Avian Bornaviruses Escape Recognition by the Innate Immune System [PDF]

open access: yes, 2010
Like other pathogens that readily persist in animal hosts, members of the Bornaviridae family have evolved effective mechanisms to evade the innate immune response.
Kothlow, Sonja   +18 more
core   +1 more source

Isolation and characterization of WUPyV in polarized human airway epithelial cells

open access: yesBMC Infectious Diseases, 2020
Background Washington University polyomavirus (WUPyV) is a novel human polyomavirus detected in childwith acute respiratory infection in 2007. However, the relationship between WUPyV and respiratory diseases has yet to be established for lacking of a ...
Chao Wang   +7 more
doaj   +1 more source

Observing micro-evolutionary processes of viral populations at multiple scales [PDF]

open access: yes, 2013
Advances in sequencing technology coupled with new integrative approaches to data analysis provide a potentially transformative opportunity to use pathogen genome data to advance our understanding of transmission.
Orton, Richard J.   +19 more
core   +1 more source

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