Results 31 to 40 of about 1,330,033 (311)

Effect of the initial dose of foot-and-mouth disease virus on the early viral dynamics within pigs

, 2009
This paper investigates the early viral dynamics of foot-and-mouth disease (FMD) within infected pigs. Using an existing within-host model, we investigate whether individual variation can be explained by the effect of the initial dose of FMD virus. To do
Nicholas J. Savill, Alexandersen, Soren, Quan, Melvyn, Quan, M., Melvyn Quan, Louise Matthews, Howey, R., Matthews, L., Savill, Nicholas J., Matthews, Louise, Savill, N.J., Howey, Richard, Mark Woolhouse, Woolhouse, Mark; id_orcid, Søren Alexandersen, Woolhouse, M., Alexandersen, S., Richard Howey   +17 more
core   +1 more source

Microneedle patch as a new platform to effectively deliver inactivated polio vaccine and inactivated rotavirus vaccine

npj Vaccines, 2022
We recently reported a lack of interference between inactivated rotavirus vaccine (IRV) and inactivated poliovirus vaccine (IPV) and their potential dose sparing when the two vaccines were administered intramuscularly either in combination or standalone ...
Sung-Sil Moon, Marly Richter-Roche, Theresa K. Resch, Yuhuan Wang, Kimberly R. Foytich, Houping Wang, Bernardo A. Mainou, Winston Pewin, Jeongwoo Lee, Sebastien Henry, Devin V. McAllister, Baoming Jiang   +11 more
doaj   +1 more source

Isolation of a Novel Bat Rhabdovirus with Evidence of Human Exposure in China

mBio, 2022
Bats are well-recognized reservoirs of zoonotic viruses. Several spillover events from bats to humans have been reported, causing severe epidemic or endemic diseases including severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), SARS-CoV, Middle
Li-Li Li, Ya-Long Xu, Xue-Xin Lu, Hong-Yan Deng, Jin-Song Li, Jing-Dong Song, Xiao-Hua Ma, Wu-Yang Zhu, Jing-Lin Wang, Zhao-Jun Duan   +9 more
doaj   +1 more source

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity

, 2011
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...
Paul Klenerman, Malte Heeg, John, Mina, Pfafferott, K, James, Ian, Ulsenheimer, Axel, Helmut M. Diepolder, Lucas, A.D., Silvana Gaudieri, Heeg, M, Rauch, A, Ian James, John, M., Andri Rauch, Klenerman, P., James, I, Simon Mallal, Diepolder, HM, Heeg, Malte, John, M, Mallal, Simon, Lucas, Andrew, Nolan, D., Lucas, M., Heeg, M., Michaela Lucas, Diepolder, H.M., Mallal, S., Gaudieri, S, Lucas, M, Gaudieri, S., Nolan, David, Ulsenheimer, A, Lucas, A, David Nolan, Klenerman, Paul, Diepolder, Helmut M., Pfafferott, K., Klenerman, P, Rauch, A., Ulsenheimer, A., Pfafferott, Katja, Lucas, Michaela, Katja Pfafferott, Andrew Lucas, Rauch, Andri, Diepolder, Helmut M, Axel Ulsenheimer, Mina John, Helmut M Diepolder, Nolan, D, Mallal, S, James, I., Gaudieri, Silvana   +53 more
core   +1 more source

Molecular evolution and genetic diversity analysis of SFTS virus based on next-generation sequencing

Biosafety and Health, 2021
SFTS virus (SFTSV) is a novel bunyavirus, which was discovered as the etiological agent of severe fever with thrombocytopenia syndrome (SFTS) in China in 2009, and was now prevalent in at least 25 provinces in China.
Aqian Li, Lin Liu, Wei Wu, Yang Liu, Xiaoxia Huang, Chuan Li, Di Liu, Jiandong Li, Shiwen Wang, Dexin Li, Mifang Liang   +10 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Abnormal upregulation of cardiovascular disease biomarker PLA2G7 induced by proinflammatory macrophages in COVID-19 patients

Scientific Reports, 2021
High rate of cardiovascular disease (CVD) has been reported among patients with coronavirus disease 2019 (COVID-19). Importantly, CVD, as one of the comorbidities, could also increase the risks of the severity of COVID-19.
Yang Li, Yongzhong Jiang, Yi Zhang, Naizhe Li, Qiangling Yin, Linlin Liu, Xin Lv, Yan Liu, Aqian Li, Bin Fang, Jiajia Li, Hengping Ye, Gang Yang, Xiaoxian Cui, Yang Liu, Yuanyuan Qu, Chuan Li, Jiandong Li, Dexin Li, Zhongtao Gai, Shiwen Wang, Faxian Zhan, Mifang Liang   +22 more
doaj   +1 more source

Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein [PDF]

, 1996
Two myxoma virus-rabbit hemorrhagic disease virus (RHDV) recombinant viruses were constructed with the SG33 strain of myxoma virus to protect rabbits against myxomatosis and rabbit viral hemorrhagic disease.
Milon, Alain, Le Gall, Ghislaine, Petit, Frédérique, Bertagnoli, Stéphane, Vautherot, Jean-François, Boilletot, E., Laurent, S., Boucraut-Baralon, Corine, Le Gall, G., Gelfi, Jacqueline, Laurent, Sylvie, Petit, F., Boilletot, Eric, Rasschaert, Denis   +13 more
core  

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Epidemiological characteristics of imported respiratory infectious diseases in China, 2014‒2018

Infectious Diseases of Poverty, 2022
Background With the progress of globalization, international mobility increases, greatly facilitating cross-border transmission of respiratory infectious diseases (RIDs).
Jin-Long Wang, Tao Chen, Le-Le Deng, Ya-Jun Han, Da-Yan Wang, Li-Ping Wang, Guang-Xue He   +6 more
doaj   +1 more source