Results 41 to 50 of about 1,791,271 (145)

Endogenous Viral Etiology of Prion Diseases [PDF]

open access: yes, 2009
Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of incurable neurodegenerative disorders, including Kuru and Creutzfeldt-Jakob disease in humans, “mad cow” disease in cattle, and scrapie in sheep. This paper
Claudiu I. Bandea
core   +1 more source

Polymicrobial periodontal disease triggers a wide radius of effect and unique virome. [PDF]

open access: yes, 2020
Periodontal disease is a microbially-mediated inflammatory disease of tooth-supporting tissues that leads to bone and tissue loss around teeth. Although bacterially-mediated mechanisms of alveolar bone destruction have been widely studied, the effects of
Gao, Li   +12 more
core  

Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]

open access: yes, 2017
Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N   +4 more
core   +3 more sources

A stochastic multi-scale model of HIV-1 transmission for decision-making: application to a MSM population. [PDF]

open access: yes, 2013
BackgroundIn the absence of an effective vaccine against HIV-1, the scientific community is presented with the challenge of developing alternative methods to curb its spread.
Cumberland, William G   +2 more
core   +2 more sources

The stability analyses of the mathematical models of hepatitis C virus infection [PDF]

open access: yes, 2015
There are two mathematical models of Hepatitis C virus (HCV) being discussed; the original model of HCV viral dynamics (Neumann et al., 1998) and its extended model (Dahari et al., 2007). The key aspects of the mathematical models have provided resources
Chong, Maureen Siew Fang   +3 more
core   +1 more source

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

open access: yes, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence   +2 more
core   +2 more sources

Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART

open access: yes, 2004
When highly active antiretroviral therapy is administered for long periods of time to HIV-1 infected patients, most patients achieve viral loads that are ``undetectable'' by standard assay (i.e., HIV-1 RNA $ < 50$ copies/ml).
Jones, Laura E., Perelson, Alan S.
core   +1 more source

In vitro amplification of BVDV field strains isolated in Argentina: effect of cell line and culture conditions [PDF]

open access: yes, 2009
The aim of this work was to study the in vitro amplification of BVDV (Pestivirus, Flaviridae) field isolates from Argentina in MDBK, BoTur and BHK-21 continuous cell lines.
Boynak, Natalia   +5 more
core  

Identification of a Proliferation Gene Cluster Associated with HPV E6/E7 Expression Level and Viral DNA Load in Invasive Cervical Carcinoma

open access: yes, 2005
Specific HPV DNA sequences are associated with more than 90% of invasive carcinomas of the uterine cervix. Viral E6 and E7 oncogenes are key mediators in cell transformation by disrupting TP53 and RB pathways. To investigate molecular mechanisms involved
Anne de La Rochefordière   +15 more
core   +1 more source

Allergens, germs and asthma [PDF]

open access: yes, 2015
Objective To explore asthma pathogenesis using data from upper and lower airways. Data Source English-language papers on human asthma and nasal polyp subjects from 1990 onwards.
Scadding, GK
core  

Home - About - Disclaimer - Privacy