Results 261 to 270 of about 2,646,395 (299)

Arctic an Unexpected Hotspot for Viral Diversity [PDF]

Nature Reviews Microbiology, 2019
This study reports the findings of a large global survey of the ecological diversity of viruses in the oceans and shows that the Arctic ocean is an unexpected hotspot for viral diversity.
Rebecca Kelsey
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Unity and diversity among viral kinases

Gene, 2020
Viral kinases are known to undergo autophosphorylation and also phosphorylate viral and host substrates. Viral kinases have been implicated in various diseases and are also known to acquire host kinases for mimicking cellular functions and exhibit virulence.
Chintalapati Janaki, Manoharan Malini, Nidhi Tyagi, Narayanaswamy Srinivasan   +3 more
openaire   +3 more sources

Viral diversity in acute infection

Nature Reviews Microbiology, 2020
This study reported the diversity of CMV, HIV-1 and RSV viral populations during acute infection from clinical samples.
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Within-Host Viral Diversity: A Window into Viral Evolution

Annual Review of Virology, 2020
The evolutionary dynamics of a virus can differ within hosts and across populations. Studies of within-host evolution provide an important link between experimental studies of virus evolution and large-scale phylodynamic analyses. They can determine the extent to which global processes are recapitulated on local scales and how accurately experimental ...
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Structural and functional diversity of viral IRESes

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2009
Some 20 years ago, the study of picornaviral RNA translation led to the characterization of an alternative mechanism of initiation by direct ribosome binding to the 5' UTR. By using a bicistronic vector, it was shown that the 5' UTR of the poliovirus (PV) or the Encephalomyelitis virus (EMCV) had the ability to bind the 43S preinitiation complex in a 5'
Laurent, Balvay, Ricardo, Soto Rifo, Emiliano P, Ricci, Didier, Decimo, Théophile, Ohlmann   +4 more
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Diversity Analysis in Viral Metagenomes

Methods in Molecular Biology, 2018
Viruses are the most abundant and diverse biological entity in the earth. Nowadays, there are several viral metagenomes from different ecological niches which have been used to characterize new viral particles and to determine their diversity. However, viral metagenomic data have the disadvantage to be high-dimensional compositional and sparse.
exaly   +3 more sources

HIV-1 superinfection and viral diversity

AIDS, 2004
Sequential acquisition of viral variants, or HIV-1 superinfection, has been proposed to explain the high fractions of recombinant viruses observed in some geographical regions, but only a few cases of superinfection in humans have been reported. Animal models suggest that susceptibility to superinfection may be restricted to a short period of time ...
Kimber L, Gross, Travis C, Porco, Robert M, Grant   +2 more
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Viral diversity and dynamics in an infant gut

Research in Microbiology, 2008
Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula,
Breitbart, Mya, Haynes, Matthew, Kelley, Scott, Angly, Florent, Edwards, Robert, Felts, Ben, Mahaffy, Joseph, Mueller, Jennifer, Nulton, James, Rayhawk, Steve, Rodriguez-Brito, Beltran, Salamon, Peter, Rohwer, Forest   +12 more
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The Role of Viral Diversity in HIV Pathogenesis

Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology, 1995
From the time of seroconversion, patients who retain a high viral load are known to progress more rapidly to AIDS than individuals who have lower levels of HIV. Increased viral load is accompanied by decreasing CD4 cell numbers, and CD4 cell counts are therefore widely used as a diagnostic marker or predictor of progression in HIV patients.
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Diversity and distribution of viral zoonosis in Africa

Virology
Viral zoonoses pose a significant public health challenge in Africa, characterized by a diverse array of pathogens transmitted from animals to humans. This review maps the geographic distribution of zoonotic viral diseases in Africa, including rodent-borne, bat-borne, tick-borne, mosquito-borne, and sandfly-associated viral zoonoses, along with those ...
Ayman Ahmed, Nouh Saad Mohamed, Emmanuel Edwar Siddig   +2 more
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