Results 181 to 190 of about 60,752 (282)

Cross‐protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objectives To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with Strangvac®, a ...
Romain Paillot, J. Richard Newton, Sonia Gonzalez Medina, Sara Frosth, Lars Frykberg, Margareta Flock, Bengt Guss, Jan‐Ingmar Flock, Andrew S. Waller   +8 more
wiley   +1 more source

Editorial: Emerging and re-emerging animal viruses: advances in diagnosis, pathogenesis, and control strategies. [PDF]

Front Cell Infect Microbiol
Chand K, Ahuja A, Dahiya SS, Saxena V.
europepmc   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security. [PDF]

Infect Drug Resist
Olwit G, Ombongi IB, Ataryeba H, Nantongo A, Shamim B.   +4 more
europepmc   +1 more source

A PD‐L1 Nanobody‐Engineered Synthetic RNA Virus Enhances Hepatocellular Carcinoma Immunotherapy by Interfering PCSK9 and Upregulating MHC‐I

Exploration, EarlyView.
A PD‐L1 nanobody‐engineered synthetic RNA virus (αPDL1‐VLPs/shPCSK9) is fabricated to inhibit PCSK9 and upregulate MHC‐I to facilitate T cells recognition of hepatocellular carcinoma (HCC). Moreover, αPDL1‐VLPs/shPCSK9 can recognize PD‐L1 and block the PD‐1/PD‐L1 pathway to prevent immune evasion, while promoting M2‐to‐M1 macrophages polarization ...
Chuyu Huang, Yun Ye, Yi Guo, Guozheng Liao, Linyi Luo, Lingwen Ding, Yingling Miao, Linping Zhao, Yongchang Ouyang, Shiying Li   +9 more
wiley   +1 more source

Norovirus on Cruise Ships: A Recurring Sentinel Event. [PDF]

Cureus
Deo AP, Thakur N, Mohi GK.
europepmc   +1 more source

Comprehensive Review on Advancements in Food Preservation Technologies for Quality and Sustainability

Food Chemistry International, EarlyView.
Preservatives limit microbial development, oxidation, and enzymatic degradation, resulting in better food quality and extended shelf life. Classified as natural, synthetic, or biological, each preservative has distinctive attributes and modes of action. Growing preference for natural preservatives aligns with clean label trends.
Monica Suresh, Arun Meyyazhagan, Haripriya Kuchi Bhotla, Manikantan Pappuswamy, Balamuralikrishnan Balasubramanian   +4 more
wiley   +1 more source

Genetic Variability and Evolutionary Dynamics of A(H1N1)pdm09 in Italy Before, During, and After the COVID-19 Pandemic. [PDF]

Pathogens
Perra M, Deplano I, Azzena I, Locci C, Ceccarelli G, Yon DK, Branda F, Ciccozzi M, Casu M, Borsetti A, Sanna D, Scarpa F.   +11 more
europepmc   +1 more source

Engineered molecular diagnostic strategies for hepatocellular carcinoma: Integrating flexible photonic barcodes, liquid biopsies, and AI‐enhanced sensing platforms

FlexMat, EarlyView.
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue, Wanqi Yang, Xiaoyu Liu, Xuehui Chu, Wei Li, Jinglin Wang   +5 more
wiley   +1 more source

Early warning of serotype replacement, spatial risk redistribution, and shifting clinical phenotypes: Insights from the 2023-2025 dengue outbreak in Meta, Colombia. [PDF]

PLoS Negl Trop Dis
Montilla Rodríguez LM, García-Balaguera C, Campo Palacio S, Bonilla Montes D, Cadena Díaz YD, Mosquera Tocora PA, Pavas Escobar NC, Andrade Carreño C, Andrade Miranda EV, Gonzalez Robayo MS.   +9 more
europepmc   +1 more source