Results 181 to 190 of about 141,914 (260)

Engineering precision oncology: Targeting tumors and immune cells with lentiviral vectors. [PDF]

Mol Ther Oncol
Rossi J, Martinello C, Sorrentino R, Guyonnet-Duperat V, Amintas S, Abrey Recalde MJ, Verhoeyen E, Dabernat S.   +7 more
europepmc   +1 more source

In vivo CAR T cell generation using retargeted and functionalized lentiviral vectors with reduced immunogenicity. [PDF]

Nat Commun
Ibrahim KE, Mears KS, Allen PM, Chinai JM, Avila OI, Muscato AJ, Lane-Reticker SK, Rojas A, Knudsen NH, Chao CC, Yates KB, Manguso RT.   +11 more
europepmc   +1 more source

Isolation and Phylogenetic Analysis of Parapoxvirus orf From Outbreaks in Sheep in the Brazilian Midwest

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction This study aimed to isolate Parapoxvirus orf and characterize its genetic diversity through phylogenetic analysis in small ruminants from the state of Mato Grosso, Brazil. Methods A total of 103 scab samples were collected from sheep affected by nine contagious ecthyma outbreaks across three different mesoregions of Mato Grosso ...
Phelipe Magalhães Duarte, Maria de Nazaré Santos Ferreira, Amanda Marques Cordeiro, Sérgio Alves do Nascimento, Rita de Cássia Carvalho Maia, José Wilton Pinheiro Junior   +5 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Comparative Molecular Docking and Pharmacokinetic Profiling of Cinnamic Acid and Oleic Acid from <i>Cinnamomum verum</i> as Potential Inhibitors of Dengue Virus Proteins. [PDF]

Infect Dis Rep
Habeeb WH, Hanoush NH, Alani MT, Abdulkareem AH, Ibrahim MO, Al-Janaby MS, Ahmed MM, Abduljaleel SS, Khaleel ZM.   +8 more
europepmc   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Conserved histidine residues and the control of tick-borne encephalitis virus maturation. [PDF]

J Gen Virol
Medits-Weiss I, Roßbacher L, Springer DN, Heinz FX, Stiasny K.   +4 more
europepmc   +1 more source

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

Glia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans, Annika Mordelt, Marta Guevara‐Ferrer, Katrin Linda, Denise Duineveld, Sofia Puvogel, Marina P. Hommersom, Nicky Scheefhals, Lisa Rahm, Emma Dyke, Gijs‐Jan Scholten, Caroline Knorz, Carlos Gonzalez Jimenez, Noelle van Egmond, Astrid Oudakker, Chantal Bijnagte‐Schoenmaker, Hans van Bokhoven, Wei Wei, Samuel Hofmann, Sabine Jung‐Klawitter, Sandra Mojica‐Perez, Jack Parent, Lidia Carotenuto, Sarah Weckhuysen, Nadine Maas, Ype Elgersma, Eline van de Ven, Dirk Lefeber, Anita Lygeroudi, Helga E. de Vries, Luc Jordi, Magdalini Polymenidou, Teresa Mitchell‐Garcia, Iulia Dragan, Amalia Dolga, Lot D. de Witte, Clara D. M. van Karnebeek, James Ellis, Alejandro Garanto, Nael Nadif Kasri   +39 more
wiley   +1 more source

Optimizing In Vivo CAR T-cell Engineering for Cancer Immunotherapy. [PDF]

Cancer Res
Wang R, Yu J, Caligiuri MA, Ma S.
europepmc   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

MedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng, Zhipeng Shen, Yuanfang Wu, Xingze Huang, Zhongyuan Zhang, Jiangyu Liu, Qichun Wei, Wenhao Chen, Ye Chen, Liang Xu   +9 more
wiley   +1 more source