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Structural characterization of viral envelope proteins

2022
Infection by viruses having lipid bilayer envelopes proceeds through the fusion of the viral envelope with a membrane of the host cell. This reaction is catalyzed by viral envelope proteins, which are exposed on the virus surface. Viral envelope proteins are responsible for the two major steps in virus entry: 1)attachment to cellular receptor/s and 2 ...
openaire   +1 more source

Cellular and viral components that mediate glucocorticoid-regulated processing of retroviral envelope proteins

Cell Biophysics, 1991
A comparison of the MMTV and MuLVenelope proteins in W7MG1 cells indicates that within the same cell some proteins are processed and sorted constitutively in the ER/Golgi system, whereas other proteins are processed in a hormone-dependent manner. The requisite hormone-dependent step in MMTV envelope protein processing occurs relatively early in the ...
M R, Stallcup, J L, Corey, R M, Bedgood
openaire   +2 more sources

Enhanced cellular secretion of AAV2 by expression of foreign viral envelope proteins

Biochemical Engineering Journal, 2015
Abstract Recombinant adeno-associated virus (rAAV), a non-enveloped virus, is widely used in gene therapy clinical trials because it does not cause human disease, transduces both dividing and non-dividing cells, and mediates stable transgene expression for years in post-mitotic tissue.
Melissa A. Kotterman   +6 more
openaire   +1 more source

Dengue viral envelope protein and histidine protonation

2009
In enveloped viruses, like flaviviruses, that enter cells via receptor-mediated endocytosis, fusion is initiated in low-pH of the endosomal vesicle. Upon appropriate triggering, the fusion protein interacts with the target membrane through a hydrophobic fusion peptide and undergoes a conformational change that drives the membrane fusion reaction1.
Yennamalli, RM   +4 more
openaire   +1 more source

The autophagy machinery interacts with EBV capsids during viral envelope release

Proceedings of the National Academy of Sciences of the United States of America, 2023
Michael Stumpe   +2 more
exaly  

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