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Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins

Current Gene Therapy, 2016
Previously unidentified viruses, such as Middle East respiratory syndrome coronavirus, continue to emerge and threaten populations, while powerful new techniques have identified many new human and animal viruses. Similarly, existing viruses, from Ebola virus to chikungunya virus, are reemerging and spreading to new geographical regions.
Imke, Steffen, Graham, Simmons
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Iscom of viral envelope proteins protects against Aujeszky's disease

Veterinary Microbiology, 1989
An immunostimulating complex (iscom) containing the envelope proteins of pseudorabies virus (PRV) was prepared and its efficacy was evaluated in two experiments on sheep. In the first experiment, sheep were intramuscularly (i.m.) or intradermally (i.d.) vaccinated with PRV iscom doses varying between 1 and 81 micrograms. The vaccination was repeated on
B, Morein   +5 more
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Reconstitution of Recombinant Viral Envelope Proteins

2003
Publisher Summary Liposomes comprising lipid bilayer membranes enclosing aqueous internal compartments serve as attractive models for reconstitution of a variety of membrane proteins such as viral envelope proteins. The lipid membranes consist of amphipathic lipids that are similar to those found in authentic cell membranes.
Christian, Oker-Blom, Matti, Vuento
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Membrane destabilization by N-terminal peptides of viral envelope proteins

The Journal of Membrane Biology, 1992
The fusion of lipid enveloped viruses with cellular membranes is thought to be mediated by the insertion into the target membrane of the N-terminal polypeptides of viral spike glycoproteins. Since membrane destabilization is a necessary step in membrane fusion, we investigated whether synthetic peptides with amino acid sequences corresponding to the N ...
N, Düzgüneş, S A, Shavnin
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Lysis of retroviruses with monoclonal antibodies against viral envelope proteins

Virology, 1980
Abstract Monoclonal antibodies identifying six independent antigenic determinants (epitopes) on the gp70 and p15(E) envelope proteins of murine leukemia virus were tested for their ability to lyse a panel of serologically different [3H]uridine-labeled retroviruses in the presence of complement.
S, Oroszlan, R C, Nowinski
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Epitope mapping of the gp53 envelope protein of bovine viral diarrhea virus

Virology, 1992
Epitopes recognized by nine monoclonal antibodies (mAbs) on the envelope protein, gp53, of two strains of bovine viral diarrhoea virus (NADL and Oregon C24V) were mapped by competitive binding assays and by the characterization and sequence analyses of mAb neutralization escape mutants.
D J, Paton, J P, Lowings, A D, Barrett
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A Dissection of Steps Leading to Viral Envelope Protein‐Mediated Membrane Fusion

Annals of the New York Academy of Sciences, 1991
increase in [Ca”] at the presynaptic nerve terminal sets a complex set of biochemical events in motion that finally terminates in the specific fusion of the membrane of the secretory vesicle with the plasma membrane.’ In studying the action of CaZ+ at the presynaptic terminal a distinction has to be made between processes that occur in the cytosol that
R, Blumenthal   +3 more
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