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Virus satellites drive viral evolution and ecology [PDF]

open access: gold, 2015
Virus satellites are widespread subcellular entities, present both in eukaryotic and in prokaryotic cells. Their modus vivendi involves parasitism of the life cycle of their inducing helper viruses, which assures their transmission to a new host. However,
Buckling, Angus   +8 more
core   +3 more sources

Statistical mechanics and thermodynamics of viral evolution

open access: gold, 2015
This paper analyzes a simplified model of viral infection and evolution using the 'grand canonical ensemble' and formalisms from statistical mechanics and thermodynamics to enumerate all possible viruses and to derive thermodynamic variables for the ...
Bianco, Simone   +3 more
core   +6 more sources

Prolonged SARS-CoV-2 Infection and Intra-Patient Viral Evolution in an Immunodeficient Child. [PDF]

open access: greenPediatr Infect Dis J, 2023
Filippi M   +18 more
europepmc   +3 more sources

Intradermal needle-free injection prevents African Swine Fever transmission, while intramuscular needle injection does not

open access: yesScientific Reports, 2023
Shared needles are a possible iatrogenic and hematogenous inanimate vector of African Swine Fever virus (ASFV) in farm conditions. To evaluate that possible transmission, sixty, 4-week-old pigs were procured from an ASF free herd free. Upon arrival, pigs
Muhammad Salman   +6 more
doaj   +1 more source

Continuous HIV-1 Escape from Autologous Neutralization and Development of Cross-Reactive Antibody Responses Characterizes Slow Disease Progression of Children

open access: yesVaccines, 2021
The antibodies with different effector functions evoked by Human Immunodeficiency Virus type 1 (HIV-1) transmitted from mother to child, and their role in the pathogenesis of infected children remain unresolved. So, too, the kinetics and breadth of these
Stefania Dispinseri   +5 more
doaj   +1 more source

Intranasal delivery of inactivated PRRSV loaded cationic nanoparticles coupled with enterotoxin subunit B induces PRRSV-specific immune responses in pigs

open access: yesScientific Reports, 2022
This study was conducted to evaluate the induction of systemic and mucosal immune responses and protective efficacy following the intranasal administration of inactivated porcine reproductive and respiratory syndrome virus (PRRSV) loaded in polylactic ...
Puwich Chaikhumwang   +4 more
doaj   +1 more source

Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

open access: yesNature Communications, 2021
Antibody responses are critical for protection from developing severe COVID-19 following SARS-CoV-2 infection. Here the authors show that antibody responses against SARS-CoV-2 spike protein correlate with neutralizing capacity and protection, are not ...
Stefania Dispinseri   +19 more
doaj   +1 more source

Evolution is Viral: The Theory of Collective Discontinuous Evolution [PDF]

open access: yes, 2010
Herein will be discussed the problems associated with the origin of species according to Darwinist processes of individual mutations. We will argue that individual mutations cannot be the driving force of species origination.
Iosif M. Gershteyn   +1 more
core   +2 more sources

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