Results 21 to 30 of about 4,157,307 (334)

Coronaviruses in humans and animals: the role of bats in viral evolution

open access: yesEnvironmental science and pollution research international, 2021
Bats act as a natural reservoir for many viruses, including coronaviruses, and have played a crucial epidemiological role in the emergence of many viral diseases. Coronaviruses have been known for 60 years.
A. El-Sayed, Mohamed Kamel
semanticscholar   +1 more source

Chronic SARS-CoV-2 infection and viral evolution in a hypogammaglobulinaemic individual.

open access: yesmedRxiv, 2021
There is widespread interest in the capacity for SARS-CoV-2 evolution in the face of selective pressures from host immunity, either naturally acquired post-exposure or from vaccine acquired immunity.
M. Williamson   +18 more
semanticscholar   +1 more source

The genomes of nucleocytoplasmic large DNA viruses: viral evolution writ large

open access: yesMicrobial Genomics, 2021
The nucleocytoplasmic large DNA viruses (NCLDVs) are a diverse group that currently contain the largest known virions and genomes, also called giant viruses. The first giant virus was isolated and described nearly 20 years ago.
Heli A. M. Mönttinen   +3 more
semanticscholar   +1 more source

Viral evolution and epidemiology [PDF]

open access: yesCurrent Opinion in Infectious Diseases, 1997
This review highlights recent research on viral evolution and its use towards understanding disease pathogenesis and epidemiology. The development of techniques such as enzymatic amplification of viral genomes and automated sequencing has led to a dramatic increase in the amount of sequence information from clinical samples. These sequences (RNA or DNA,
Katrin, Leitmeyer, Rebeca, Rico-Hesse
openaire   +2 more sources

Continuous HIV-1 Escape from Autologous Neutralization and Development of Cross-Reactive Antibody Responses Characterizes Slow Disease Progression of Children

open access: yesVaccines, 2021
The antibodies with different effector functions evoked by Human Immunodeficiency Virus type 1 (HIV-1) transmitted from mother to child, and their role in the pathogenesis of infected children remain unresolved. So, too, the kinetics and breadth of these
Stefania Dispinseri   +5 more
doaj   +1 more source

SARS‐CoV‐2 biology and variants: anticipation of viral evolution and what needs to be done

open access: yesEnvironmental Microbiology, 2021
Summary The global propagation of SARS‐CoV‐2 and the detection of a large number of variants, some of which have replaced the original clade to become dominant, underscores the fact that the virus is actively exploring its evolutionary space.
Ruibang Luo   +3 more
semanticscholar   +1 more source

Controlling long-term SARS-CoV-2 infections can slow viral evolution and reduce the risk of treatment failure

open access: yesScientific Reports, 2021
The rapid emergence and expansion of novel SARS-CoV-2 variants threatens our ability to achieve herd immunity for COVID-19. These novel SARS-CoV-2 variants often harbor multiple point mutations, conferring one or more evolutionarily advantageous traits ...
D. Van Egeren   +7 more
semanticscholar   +1 more source

Intranasal delivery of inactivated PRRSV loaded cationic nanoparticles coupled with enterotoxin subunit B induces PRRSV-specific immune responses in pigs

open access: yesScientific Reports, 2022
This study was conducted to evaluate the induction of systemic and mucosal immune responses and protective efficacy following the intranasal administration of inactivated porcine reproductive and respiratory syndrome virus (PRRSV) loaded in polylactic ...
Puwich Chaikhumwang   +4 more
doaj   +1 more source

Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

open access: yesNature Communications, 2021
Antibody responses are critical for protection from developing severe COVID-19 following SARS-CoV-2 infection. Here the authors show that antibody responses against SARS-CoV-2 spike protein correlate with neutralizing capacity and protection, are not ...
Stefania Dispinseri   +19 more
doaj   +1 more source

Evolution is Viral: The Theory of Collective Discontinuous Evolution [PDF]

open access: yes, 2010
Herein will be discussed the problems associated with the origin of species according to Darwinist processes of individual mutations. We will argue that individual mutations cannot be the driving force of species origination.
Iosif M. Gershteyn   +1 more
core   +2 more sources

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