Results 31 to 40 of about 4,157,307 (334)
Scientific Reports, 2022 Porcine deltacoronavirus (PDCoV) and porcine epidemic diarrhea virus (PEDV) infect the small intestine and cause swine enteric coronavirus disease. The mucosal innate immune system is the first line of defense against viral infection.
Kepalee Saeng-chuto +5 more
doaj +1 more source
The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase
mBio, 2010 The swine-origin H1N1 influenza A virus emerged in early 2009 and caused the first influenza pandemic in 41 years. The virus has spread efficiently to both the Northern and the Southern Hemispheres and has been associated with over 16,000 deaths.
Brett W. Jagger +10 more
doaj +1 more source
Learning the language of viral evolution and escape
Science, 2020 Natural language predicts viral escape Viral mutations that evade neutralizing antibodies, an occurrence known as viral escape, can occur and may impede the development of vaccines. To predict which mutations may lead to viral escape, Hie et al.
Brian L. Hie +3 more
semanticscholar +1 more source
Wolbachia versus dengue: Evolutionary forecasts. [PDF]
, 2013 A novel form of biological control is being applied to the dengue virus. The agent is the maternally transmitted bacterium Wolbachia, naturally absent from the main dengue vector, the mosquito Aedes aegypti.
Bull, James J, Turelli, Michael
core +1 more source
Physics of Life Reviews, 2006 In the last two decades, viruses have been used as model systems to study evolution in short periods of time. Due to their characteristics, virus adapt rapidly to changing conditions, thus allowing the quantification of several evolutionary features under controlled laboratory conditions.
Manrubia Cuevas, Susanna, Lázaro, Ester
openaire +2 more sources
Viral diseases and human evolution [PDF]
Memórias do Instituto Oswaldo Cruz, 2000 The interaction of man with viral agents was possibly a key factor shaping human evolution, culture and civilization from its outset. Evidence of the effect of disease, since the early stages of human speciation, through pre-historical times to the present suggest that the types of viruses associated with man changed in time.
Élcio de Souza Leal +1 more
openaire +4 more sources
EMBO Molecular Medicine, 2013 The gastrointestinal tract is a principal route of entry and site of persistence of human immunodeficiency virus type 1 (HIV‐1). The intestinal mucosa, being rich of cells that are the main target of the virus, represents a primary site of viral ...
Mariangela Cavarelli +3 more
doaj +1 more source
mBio, 2015 Influenza virus infections are a global public health problem, with a significant impact of morbidity and mortality from both annual epidemics and pandemics.
Louis M. Schwartzman +5 more
doaj +1 more source
iScience, 2022 Summary: The difficulty to unambiguously identify the various subsets of mononuclear phagocytes (MNPs) of the intestinal lamina propria has hindered our understanding of the initial events occurring after mucosal exposure to HIV-1.Here, we compared the ...
Mariangela Cavarelli +10 more
doaj +1 more source
Longitudinal sequencing of HIV-1 infected patients with low-level viremia for years while on ART shows no indications for genetic evolution of the virus [PDF]
, 2017 HIV-infected patients on antiretroviral therapy (ART) may present low-level viremia (LLV) above the detection level of current viral load assays.
Dauwe, Kenny +7 more
core +1 more source