Results 91 to 100 of about 299,195 (309)

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Community perceptions of a malaria vaccine in the Kintampo districts of Ghana. [PDF]

, 2013
BACKGROUND: Malaria remains the leading cause of morbidity and mortality in sub-Saharan Africa despite tools currently available for its control. Making malaria vaccine available for routine use will be a major hallmark, but its acceptance by community ...
A Bingham, A Dodoo, A Launiala, A Olotu, AK Rowe, AS Jegede, C Wongsrichanalai, CA Baume, CA de Quadros, Dan-Bright S Dzorgbo, DB Dery, DI Ojakaa, E Klinkenberg, F Nuwaha, FN Binka, G GSS, Kojo A Senah, KP Asante, Kwaku P Asante, Lawrence G Febir, PW Chung, RW Snow, S Owusu-Agyei, S Owusu-Agyei, S Owusu-Agyei, Seth Owusu-Agyei, ST Agnandji, ST Agnandji, TE Nkya, Timothy S Letsa, WHO   +30 more
core   +2 more sources

Parasitology [PDF]

, 2005
Concomitant infections are common in nature and often involve parasites. A number of examples of the interactions between protozoa and viruses, protozoa and bacteria, protozoa and other protozoa, protozoa and helminths, helminths and viruses, helminths ...
Cox, F, Despommier, D, Gillespie, S, Wakelin, D   +3 more
core   +3 more sources

CD8+ T-cell responses in vaccination: Reconsidering targets and function in the context of chronic antigen stimulation [PDF]

, 2018
Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell-based vaccines.
Cosma, Gabriela L., Eisenlohr, Laurence
core   +2 more sources

COVID-19 vaccine immunogenicity in Mongolian adults with and without chronic hepatitis

BMC Infectious Diseases
Background Mongolia has a high prevalence of liver disease from chronic viral hepatitis infections, which can compromise the immune response. It is unclear whether people with chronic liver disease produce a robust antibody response to the COVID-19 ...
Viviane Callier, Ganbolor Jargalsaikhan, Munguntsetseg Batkhuu, Renee Ridzon, Sally Hunsberger, Irini Sereti, Kathryn Shaw-Saliba, Shera Weyers, Alyson Francis, Naranjaral Dashdorj   +9 more
doaj   +1 more source

Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]

, 2016
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico, Fiers, Walter, Saelens, Xavier, Schepens, Bert, Schotsaert, Michael, Smet, Anouk, Stegalkina, Svetlana, Vanderschaeghe, Dieter, Vogel, Thorsten U, Ysenbaert, Tine   +9 more
core   +2 more sources

Chronic hepatitis C viral infection subverts vaccine‐induced T‐cell immunity in humans

Hepatology, 2016
Adenoviral vectors encoding hepatitis C virus (HCV) nonstructural (NS) proteins induce multispecific, high‐magnitude, durable CD4+ and CD8+ T‐cell responses in healthy volunteers.
C. Kelly, Leo Swadling, S. Capone, Anthony Brown, R. Richardson, J. Halliday, Annette von Delft, Y. Oo, D. Mutimer, A. Kurioka, F. Hartnell, J. Collier, V. Ammendola, M. D. Sorbo, F. Grazioli, Marialuisa Esposito, S. D. Marco, L. Siani, C. Traboni, A. Hill, S. Colloca, A. Nicosia, R. Cortese, A. Folgori, P. Klenerman, E. Barnes   +25 more
semanticscholar   +1 more source

The reform of the Italian legislation on childhood immunization [PDF]

, 2018
Upon the proposal of the Italian government, Law n. 191/2017 has been enacted, meant to considerably raise the number of mandatory vaccinations, while leaving several others merely "recommended" (non-mandatory).
Cocchiara, Rosario Andrea, La Torre, Giuseppe, Marinelli, Enrico, Montanari Vergallo, Gianluca, Zaami, Simona   +4 more
core   +1 more source

Immune response to vaccines in children with celiac disease [PDF]

, 2017
Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina, CHIESA, CLAUDIO, OLIVERO, FRANCESCA, PACIFICO, Lucia, Spagnolo, Alessandra   +4 more
core   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source