Results 201 to 210 of about 1,063,286 (267)

Respiratory viral infection is associated with increased <i>Pseudomonas</i> abundance in the cystic fibrosis airway. [PDF]

ERJ Open Res
Hilliam Y, Armbruster CR, Atteih SE, Rapsinski GJ, Johnson M, Moore J, Koirala J, Krainz L, Gaston J, Williams J, Cooper VS, Lee SE, Bomberger JM.   +12 more
europepmc   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

An Unexpected Diagnosis After a Viral Infection: A Case of a Giant Mediastinal Ganglioneuroma. [PDF]

Cureus
Veloso A, Fernandes A, Martins R, Santos J, Areias V.   +4 more
europepmc   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Investigating the Role of Cortical Microglia in a Mouse Model of Viral Infection-Induced Seizures. [PDF]

eNeuro
Balachandar L, Buxton L, Kearns I, Stefanic MF, Bell LA, DePaula-Silva AB, Wilcox KS.   +6 more
europepmc   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Cucumber Mosaic Virus Coat Protein Sequesters Host CDPK7-Like Into Phase-Separated Condensates to Promote Viral Infection. [PDF]

Mol Plant Pathol
Zhao L, Yang T, Zhang X, Zhao C, Song Q, Hu D, Yu L, Song R.   +7 more
europepmc   +1 more source

Haplotype-phased 'Ottawa 3' genome unravels differential reaction of apple rootstock roots to mixed viral infection. [PDF]

Plant J
Costa LC, Gottschalk C, Upchurch DM, Hurtado-Gonzales OP, Mansfeld BN, Yocca A, Whitt L, Vann C, Fazio G.   +8 more
europepmc   +1 more source

Ets1 represses Blimp1 to promote germinal center T follicular helper cell differentiation during viral infection. [PDF]

J Immunol
Perkins B, Fuchs B, Nguyen NX, Williams MA, Hale JS.   +4 more
europepmc   +1 more source