Results 251 to 260 of about 1,648,672 (312)

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Transmissible Gastroenteritis Virus Binding to Red Blood Cells Disrupts Iron Homeostasis and Promotes Viral Infection. [PDF]

Vet Sci
Xia L, Wang Z, He Y, Wang J, Ren J, Zhang E, Liu Z, Li Y, Li Z, Wei Z.   +9 more
europepmc   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Hijacking the unfolded protein response (UPR) pathway: Balancing viral infection and host cell survival. [PDF]

J Biol Chem
Chen H, Liu D, Hua J, Wu M, Hua Y, Feng C, He Z, Moffett P, Zhang K.   +8 more
europepmc   +1 more source

The function and mechanism of protein acylation in the regulation of viral infection. [PDF]

Virulence
Song L, Wei Z, Shang P, Hu S, Chen L, Niu L, Wang Y, Gan M, Shen L, Zhu L, Zhao Y.   +10 more
europepmc   +1 more source

The PSRP2/4 Proteins Promote Viral Infection by Interacting with the VPg Protein of TuMV. [PDF]

Plants (Basel)
Lyu S, Lu W, Zhang C, Wang W, Yuan M, E L, Liu T, Deng S.   +7 more
europepmc   +1 more source

Metabolomic profiling reveals the potential of fatty acids as regulators of exhausted CD8 T cells during chronic viral infection. [PDF]

Proc Natl Acad Sci U S A
Kazane KR, Labarta-Bajo L, Zangwill DR, Liimatta K, Vargas F, Weldon KC, Dorrestein PC, Zúñiga EI.   +7 more
europepmc   +1 more source

Viral infection and thyroid disorders: a narrative review. [PDF]

Front Microbiol
Li Y, Li W.
europepmc   +1 more source

Carbon dots: A promising tool for viral infection treatment. [PDF]

Mater Today Bio
Gedda G, Putta CL, Verma A, Ramesh SSR, Girma WM, Park YJ, Rengan AK, Pang MG.   +7 more
europepmc   +1 more source