Results 21 to 30 of about 3,717,929 (382)

Quantitative Detection and Viral Load Analysis of SARS-CoV-2 in Infected Patients

Clinical Infectious Diseases, 2020
Background Coronavirus disease 2019 (COVID-19) has become a public health emergency. The widely used reverse transcription PCR (RT-PCR) method has limitations for clinical diagnosis and treatment. Methods A total of 323 samples from 76 COVID-19 confirmed
Feng-ting Yu, Liting Yan, Nan Wang, Siyuan Yang, Linghang Wang, Yun-xia Tang, Gui-ju Gao, Sa Wang, Chengjie Ma, R. Xie, Fang Wang, Chianru Tan, Lingxiang Zhu, Yong Guo, Fujie Zhang   +14 more
semanticscholar   +1 more source

Viral Load Suppression after Enhanced Adherence Counseling and Its Predictors among High Viral Load HIV Seropositive People in North Wollo Zone Public Hospitals, Northeast Ethiopia, 2019: Retrospective Cohort Study

AIDS Research and Treatment, 2020
Background. The World Health Organization currently encourages enhanced adherence counseling for human immunodeficiency virus (HIV) seropositive people with a high viral load count before a treatment switch to the second-line regimen, yet little is known
Gedefaw Diress, Samuel Dagne, Birhan Alemnew, Seteamlak Adane, Amanuel Addisu   +4 more
doaj   +1 more source

How reliable is an undetectable viral load? [PDF]

HIV Medicine, 2009
Objectives An article by the Swiss AIDS Commission states that patients with stably suppressed viraemia [i.e. several successive HIV‐1 RNA plasma concentrations (viral loads, VL) below the limits of detection during 6 months or more of highly active antiretroviral therapy (HAART)] are unlikely to be infectious.
Combescure, Christophe, Vallier, N., Ledergerber, B., Cavassini, M., Furrer, H., Rauch, A., Battegay, M., Bernasconi, E., Vernazza, P., Hirschel, B.   +9 more
openaire   +4 more sources

SARS-CoV-2 viral load is associated with increased disease severity and mortality

Nature Communications, 2020
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 viral load from participants with a diverse range of COVID-19 disease severity ...
Jesse Fajnzylber, J. Regan, Kendyll Coxen, H. Corry, Colline Wong, A. Rosenthal, Daniel P. Worrall, Francoise F. Giguel, A. Piechocka-Trocha, C. Atyeo, S. Fischinger, Andrew T. Chan, K. Flaherty, K. Hall, M. Dougan, E. Ryan, Elizabeth Gillespie, Rida Chishti, Yijia Li, N. Jilg, D. Hanidziar, R. Baron, L. Baden, Athe M Tsibris, K. Armstrong, D. Kuritzkes, G. Alter, B. Walker, Xu Yu, Jonathan Z. Li, Betelihem A. (Betty) Patrick Diane Alejandro Julia Max Yanni Abayneh Allen Antille Balazs Bals Barbash Bartsch , B. A. Abayneh, P. Allen, Diane Antille, A. Balazs, Julia Bals, M. Barbash, Y. Bartsch, J. Boucau, Siobhan Boyce, J. Braley, Karen Branch, Katherine T. Broderick, J. Carney, Joshua M. Chevalier, M. Choudhary, Navin Chowdhury, T. Cordwell, G. Daley, Susan P Davidson, Michaël Desjardins, Lauren Donahue, David A. Drew, Kevin B. Einkauf, Sampson Elizabeth, Ashley Elliman, B. Etemad, Jonathan K. Fallon, Liz Fedirko, Kelsey K. Finn, J. Flannery, Pamela J Forde, Pilar Garcia-Broncano, E. Gettings, David Golan, Kirsten Goodman, A. Griffin, S. Grimmel, Kathleen A. Grinke, C. Hartana, Michael D Healy, H. Heller, Deborah Henault, Grace Holland, Chenyan Jiang, Hannah Jordan, P. Kaplonek, E. Karlson, Marshall Karpell, Chantal Kayitesi, E. Lam, V. LaValle, Kristina Lefteri, Xiaodong Lian, M. Lichterfeld, D. Lingwood, Hang Liu, Jinqing Liu, Kelly Lopez, Yuting Lu, Sarah Luthern, Ngoc L. Ly, Maureen MacGowan, Karen Magispoc, J. Marchewka, Brittani Martino, R. McNamara, Ashlin R. Michell, Ilan Millstrom, Noah Miranda, Christian Nambu, S. Nelson, Marjorie Noone, L. Novack, C. O’Callaghan, Christine Ommerborn, Matt Osborn, Lois Chris Pacheco, Nicole Phan, S. Pillai, F. A. Porto, Yelizaveta Rassadkina, Alexandra Reissis, Francis Ruzicka, Kyra W. Seiger, K. Selleck, Libera Sessa, A. Sharpe, C. Sharr, Sally A. Shin, Nishant K. Singh, Sue Slaughenhaupt, K. Sheppard, Weiwei Sun, Xiaoming Sun, Elizabeth Suschana, Opeyemi Talabi, Hannah Ticheli, S. Weiss, Vivine Wilson, A. Zhu   +130 more
semanticscholar   +1 more source

Viral load detection and management on first line ART in rural Rwanda

BMC Infectious Diseases, 2019
Background To achieve the ambitious 90–90-90 UNAIDS targets, access to routine viral load (VL) is critical. To measure VL, Rwanda has relied on a national reference laboratory for years.
Jean de Dieu Ndagijimana Ntwali, Tom Decroo, Muhayimpundu Ribakare, Athanase Kiromera, Placidie Mugwaneza, Sabin Nsanzimana, Lutgarde Lynen   +6 more
doaj   +1 more source

Estimating epidemiologic dynamics from cross-sectional viral load distributions

Science, 2021
Added value of PCR testing for COVID-19 During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, polymerase chain reaction (PCR) tests were generally reported only as binary positive or negative outcomes.
J. Hay, L. Kennedy‐Shaffer, S. Kanjilal, N. Lennon, S. Gabriel, M. Lipsitch, M. Mina   +6 more
semanticscholar   +1 more source

Measuring Population Transmission Potential for HIV: An Alternative Metric of Transmission Risk in Men who have Sex with Men (MSM) in the US [PDF]

, 2012
Background Various metrics for HIV burden and treatment success [e.g. HIV prevalence, community viral load (CVL), population viral load (PVL), percent of HIV-positive persons with undetectable viral load] have important public health limitations for ...
del Rio, Carlos, Frew, Paula M., Kelley, Colleen F., O\u27Hara, Brandon M., Peterson, John L., Rosenberg, Eli S., Sanchez, Travis, Sullivan, Patrick S.   +7 more
core   +2 more sources

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load on Risk of Intubation and Mortality Among Hospitalized Patients With Coronavirus Disease 2019

Clinical Infectious Diseases, 2020
Background Patients hospitalized with coronavirus disease 2019 (COVID-19) frequently require mechanical ventilation and have high mortality rates. However, the impact of viral burden on these outcomes is unknown.
Reed Magleby, L. Westblade, Alex Trzebucki, M. Simon, M. Rajan, Joel C Park, P. Goyal, M. Safford, M. Satlin   +8 more
semanticscholar   +1 more source

Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization

npj Biofilms and Microbiomes, 2021
The human oral and gut commensal microbes play vital roles in the development and maintenance of immune homeostasis, while its association with susceptibility and severity of SARS-CoV-2 infection is barely understood.
Yongjian Wu, Xiaomin Cheng, Guangmin Jiang, Huishu Tang, Siqi Ming, Lantian Tang, Jiahai Lu, Cheng Guo, H. Shan, Xi Huang   +9 more
semanticscholar   +1 more source

Initial viral load and the outcomes of SARS [PDF]

Canadian Medical Association Journal, 2004
Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus. It may progress to respiratory failure, and a significant proportion of patients die. Preliminary data suggest that a high viral load of the SARS coronavirus is associated with adverse outcomes in the intensive care unit, but the relation of viral load to survival is unclear.We ...
Chan, KH, Peiris, JSM, Poon, LLM, Hung, IFN, Yuen, KY, Tse, DMW, Law, KI, Ng, PW, Sim, TC, Ng, WL, Chan, VL, Tang, BSF, Leung, WS, Wong, MML, Chan, KS, Cheng, VCC, Chu, CM   +16 more
openaire   +5 more sources