Results 111 to 120 of about 131,769 (294)

HIV viral suppression and risk of viral rebound in patients on antiretroviral therapy: a two- year retrospective cohort study in Northern Tanzania

BMC Infectious Diseases
Background The world is moving towards the third target of the Joint United Nations Programme on HIV/AIDS to ensure most people receiving antiretroviral therapy (ART) are virologically suppressed.
Monica S Kahabuka, Yimtubezinash Woldeamanuel, Peter M. Mbelele, Emmanuel A. Mpolya, Stellah G. Mpagama, Jonas P. Kessy, Tsegahun Manyazewal   +6 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

MicroRNA-29 family expression and its relation to antiviral immune response and viro-immunological markers in HIV-1-infected patients [PDF]

, 2015
BACKGROUND: Several in vitro studies suggested the microRNA-29 (miRNA-29) family is involved in regulating HIV-1 and modulating the expression of interleukin (IL)-32, an anti-HIV-1 cytokine.
ANTONELLI, Guido, Cacciotti G, D'ETTORRE, Gabriella, FALASCA, FRANCESCA, MEZZAROMA, Ivano, MONTELEONE, Katia, SCAGNOLARI, CAROLINA, SELVAGGI, CARLA, TURRIZIANI, Ombretta, VULLO, Vincenzo   +9 more
core   +2 more sources

Factors associated with viral load testing and viral suppression among HIV-positive female sex workers in Nigeria

PLOS ONE
Background Female sex workers (FSWs) are at high risk for HIV infection and face unique barriers to receiving and adhering to testing and treatment. Early viral suppression and consistent viral load testing are critical to optimizing health and reducing transmission in this population.
Kene David Nwosu, Abiye Kalaiwo, Wingston Felix Ngambi, Janne Estill, Ughweroghene Kingston Omo-Emmanuel, Godwin Emmanuel, Olivia Keiser   +6 more
openaire   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Factors associated with viral load non-suppression among adults with HIV in Sughd region, Tajikistan: a retrospective cohort study

BMC Infectious Diseases
Background Viral load suppression among people living with HIV is a key strategy for reducing HIV transmission. A global target for HIV elimination aims to have 95% of people living with HIV diagnosed, 95% of people diagnosed on antiretroviral therapy ...
Emomali Qurbonov, Dilyara Nabirova, Aisuluu Kubatova, Salomudin Yusufi, Edmond F. Maes, Roberta Horth   +5 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Treatment of Young Children with HIV Infection: Using Evidence to Inform Policymakers [PDF]

, 2012
PMCID: PMC3404108This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Abrams, EJ, Cotton, M, Gibb, DM, Mulenga, V, Musoke, P, Penazzato, M, Prendergast, AJ   +6 more
core   +3 more sources

Long-term durability of HIV viral load suppression [PDF]

The Lancet HIV, 2017
Nila J, Dharan, David A, Cooper
openaire   +2 more sources

Outcomes of patients enrolled in an antiretroviral adherence club with recent viral suppression after experiencing elevated viral loads

Southern African Journal of HIV Medicine, 2019
Eligibility for differentiated antiretroviral therapy (ART) delivery models has to date been limited to low-risk stable patients.We examined the outcomes of patients who accessed their care and treatment through an ART adherence club (AC), a differentiated ART delivery model, immediately following receiving support to achieve viral suppression after ...
Sharp, Joseph, Wilkinson, Lynne, Cox, Vivian, Cragg, Carol, van Cutsem, Gilles, Grimsrud, Anna   +5 more
openaire   +5 more sources