Immune mechanisms of group B coxsackievirus induced viral myocarditis [PDF]
Virulence, 2023 Viral myocarditis is known to be a primary cause of dilated cardiomyopathy (DCM) that can lead to heart failure and sudden cardiac death and is invariably caused by myocardial viral infection following active inflammatory destruction of the myocardium ...
Yue Zhang +4 more
doaj +2 more sources
The protective effects of ivabradine in preventing progression from viral myocarditis to dilated cardiomyopathy [PDF]
Frontiers in Pharmacology, 2016 To study the beneficial effects of ivabradine in dilated cardiomyopathy mice, which evolved from coxsackievirus B3-induced chronic viral myocarditis. Four-to-five-week-old male balb/c mice were inoculated intraperitoneally with coxsackievirus B3 (Strain ...
Li Yue-Chun +8 more
doaj +3 more sources
Myocarditis, Disseminated Infection, and Early Viral Persistence Following Experimental Coxsackievirus B Infection of Cynomolgus Monkeys [PDF]
, 2013 Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse.
Cheryl E. Cammock +7 more
core +9 more sources
Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis. [PDF]
PLoS ONE, 2014 Activation of the cholinergic anti-inflammatory pathway, which relies on the α7nAchR (alpha 7 nicotinic acetylcholine receptor), has been shown to decrease proinflammatory cytokines.
Zheng Cheng +6 more
doaj +3 more sources
In vivo delivery of adenoviral vector containing interleukin-17 receptor a reduces cardiac remodeling and improves myocardial function in viral myocarditis leading to dilated cardiomyopathy. [PDF]
PLoS ONE, 2013 Th17 cells have been implicated in the pathogenesis of myocarditis. Interleukin (IL)-17A produced by Th17 cells is dispensable for viral myocarditis but essential for the progression to dilated cardiomyopathy (DCM).
Yuquan Xie +9 more
doaj +3 more sources
Loss of TRIM29 mitigates viral myocarditis by attenuating PERK-driven ER stress response in male mice [PDF]
Nature CommunicationsViral myocarditis, an inflammatory disease of the myocardium, is a significant cause of sudden death in children and young adults. The current coronavirus disease 19 pandemic emphasizes the need to understand the pathogenesis mechanisms and potential ...
Junying Wang +8 more
doaj +2 more sources
COVID-19 Associated Acute Viral Myocarditis and Thyroid Gland Follicular Neoplasm in a Hemodialysis Patient [PDF]
Oman Medical Journal, 2023 Since the first cases were reported in Wuhan, China, COVID-19 has spread swiftly worldwide and is caused by SARS-CoV-2. The development of myocardial injury is associated with significantly worse clinical course and increased mortality.
Ahmed Atris, Issa Al Salmi, Suad Hannawi
doaj +2 more sources
Case Report: Three cases of clinically suspected viral myocarditis with recovery of left ventricular dysfunction [PDF]
Frontiers in Cardiovascular MedicineViral myocarditis is an important cause of non-ischemic cardiomyopathy. Multiple clinical manifestations have been reported, including acute heart failure, cardiogenic shock, and ventricular arrhythmias.
Jonathan Brown +7 more
doaj +2 more sources
Diagnostics, 2022 Viral myocarditis is inflammation of the myocardium secondary to viral infection. The clinical presentation of viral myocarditis is very heterogeneous and can range from nonspecific symptoms of malaise and fatigue in subclinical disease to a more florid ...
Adedayo Adeboye +4 more
doaj +1 more source
Mechanisms and Therapeutic Strategies of Viral Myocarditis Targeting Autophagy
Frontiers in Pharmacology, 2022 Viral myocarditis is caused by infection with viruses or bacteria, including coxsackievirus B3 (CVB3), and is characterized by acute or chronic inflammatory responses in the heart.
Kun Yu +11 more
doaj +1 more source