Results 131 to 140 of about 120,562 (238)

Characterization of the Cross-Resistance of SARS-CoV‑2 Main Protease Inhibitors, Ibuzatrelvir, Ensitrelvir, and Nirmatrelvir. [PDF]

ACS Pharmacol Transl Sci
Tan H, Chi X, Deng X, Wang J.
europepmc   +1 more source

Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence [PDF]

, 1986
Buchmeier, M J, Dalziel, Robert, Lampert, P W, Talbot, Pierre J   +3 more
core  

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

FUT1- and GAL3ST2-mediated cellular glycan remodeling broadly restricts sialic acid-dependent viral infections. [PDF]

Proc Natl Acad Sci U S A
Zhu X, Nakano S, Rao VN, Miranda HA, Spurrier MA, Skavicus S, Luo Z, Heaton NS.   +7 more
europepmc   +1 more source

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut   +6 more
wiley   +1 more source

Aminoquinoline surfen inhibits pseudorabies virus attachment by preventing the binding of glycoprotein C to heparan sulfate. [PDF]

Microbiol Spectr
Wang Y, Zhu B, Huang X, Zhao F, Zheng Z, Zhao S, Huang X, Zheng Y, Zhao Q, Wen Y, Wu R, Du S, Wu C, An T, Cao S.   +14 more
europepmc   +1 more source

Simultaneous expression of three G genotypes of VP7 proteins in a recombinant porcine rotavirus confers protective immunity against multiple rotavirus infections. [PDF]

J Virol
Cheng X, Deng H, Bian X, Wang J, Wang C, Han N, Zhou J, Zhu X, Zhang X, Yang X, Tao R, Li B.   +11 more
europepmc   +1 more source

Water microdroplet platforms for sustainable, reagent-free viral disinfection. [PDF]

J Biol Eng
Sheen J, Lee J, Kim Y, Lee K, Lee JK.
europepmc   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Poxvirus A52 protein subverts autophagy flux by blocking autophagosome-lysosome fusion to promote viral replication. [PDF]

PLoS Pathog
Niu K, Fang Y, Deng Y, Wang Z, Xie S, Zhu J, Song B, Wu W, Jing Z, Peng C.   +9 more
europepmc   +1 more source