Results 111 to 120 of about 84,952 (272)

Characterization of a Second Bovine Rotavirus Serotype [PDF]

, 1987
Bovine rotavirus (BRV) V 1005 was characterized by two-way cross-neutralization tests as a second serotype of BRV. Virions and inner shell particles of 65 nm and 55 nm diameter respectively, and empty capsids of 65 nm and 55 nm diameter were separated by
Fryder, V., Eichhorn, Werner, Marc-Martin, S., Sidoti, J., Büssow, Harald   +4 more
core  

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Complementary approaches to target human respiratory syncytial virus using small molecule ligands [PDF]

, 2012
In the current project, situated at the interface of chemistry and virology, complementary drug discovery approaches (high-throughput screening and structurebased drug design) have been exploited in order to discover novel small molecule inhibitors of ...
Lardeau, Charles-Hugues Claude Jean
core  

Inhibition of SCD1 impacts viral particle infectivity.

, 2018
Huh7 cells were infected with DENV2, MOI = 1 and treated with SCD1 inhibitor or DMSO. (A) Virus in supernatants (extracellular) and cell-associated virus were collected at 24 and 48hr and quantified by plaque assay.
Rushika Perera (175977), Joel Rovnak (4474531), J. Jordan Steel (499663), Dean C. Crick (364125), Venugopal Pujari (1314981), Rebekah C. Gullberg (755172)   +5 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

CellVision: A deep learning based image analysis platform to accelerate immuno-plaque assay data processing for dengue vaccine development

SLAS Discovery
Accurately detecting patterns of interest across a large number of images presents a significant challenge in data analysis for high-throughput analytical assays.
Yi Wang, Michelle N. Ngo, Shubing Wang, Justin Jarrah, Hossein Salami, Carl Hofmann, Anjali Joshi, Daniel Skomski, John W. Loughney   +8 more
doaj   +1 more source

A Modified MS2 Bacteriophage Plaque Reduction Assay for the Rapid Screening of Antiviral Plant Extracts

, 2010
Traditional methods of screening plant extracts and purified components for antiviral activity require up to a week to perform, prompting the need to develop more rapid quantitative methods to measure the ability of plant based preparations to block ...
Kalt, Fred, Ian Cock, Cock, Ian, FR Kalt
core   +1 more source

Topical treatment of equine aural plaques with nitric acid and zinc solution

Equine Veterinary Journal, EarlyView.
Abstract Background Equine aural plaque caused by equine papilloma viruses is common worldwide and affected horses can show severe clinical signs. Due to its viral aetiology, in some countries affected horses are not allowed to compete. Since lesions persist, showing no spontaneous regression, effective and safe treatment is required.
Lii Katarina Leo, Kerstin Elisabet Bergvall   +1 more
wiley   +1 more source

Evaluating Probenecid or Oseltamivir Inhibition of Influenza A Virus Replication Through Plaque Assay or Fluorescent Focus Assay Using Non-Structural Protein 1–H1N1 Venus Reporter Virus

It is essential to understand the molecular mechanisms of influenza antiviral therapeutics to evaluate their efficacy. Virus plaque assays are commonly used to assess the antiviral effects of drugs on virus replication; however, this method is labor ...
Tripp, Ralph A., Jackelyn Murray, Sancilio, Fred D., Nogales, Aitor, Martin, David E., Luis Martinez-Sobrido, Aitor Nogales, Ralph A. Tripp, Martínez-Sobrido, Luis, David E. Martin, Murray, Jackelyn, Fred D. Sancilio   +11 more
core   +1 more source