Results 111 to 120 of about 1,527,964 (244)

Viabilidade de adenovírus humano recombinante e norovírus murino em água do mar em tanques de depuração de ostras [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2014.A depuração de moluscos bivalves é um processo utilizado que resulta na expulsão
Garcia, Lucas Ariel Totaro
core  

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

Clinical Pharmacology &Therapeutics, EarlyView.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts, Xavier Woot de Trixhe, Martine Neyens, Thomas N. Kakuda, Liesbeth Van Wesenbeeck, Annemie Buelens, Freya Rasschaert, Anna Durbin, Oliver Ackaert   +8 more
wiley   +1 more source

Synthesis, characterization, cytotoxicity, and antiviral activity of new coumarin analogues against coronavirus

Results in Chemistry
Coronaviruses have emerged as a global health challenge, with the recent outbreak of SARS-CoV-2 affecting more than 600 million individuals worldwide. While vaccination remains a central preventive approach, addressing SARS-CoV-2 involves antiviral drugs,
Mohammad Auwal Sa’ad, Manickam Ravichandran, Lalitha Pattabhiraman, Shivkanya Fuloria, Veerasamy Ravichandran, Faizul Fikri Mohd Yusop, Neeraj Kumar Fuloria   +6 more
doaj   +1 more source

Single‐Cell Reporter Dynamics During the First Two Rounds of Rhinovirus Plaque Growth

Cytometry Part A, EarlyView.
ABSTRACT When infection spreads from an initially infected cell through a cell monolayer, the resulting plaque records successive rounds of virus–cell interaction. Fluorescent reporter viruses permit this process to be followed at single‐cell resolution, but whether secondary infected cells retain detectable signatures associated with their plaque of ...
Rahul Ramachandran, Huicheng Shi, John Yin   +2 more
wiley   +1 more source

Changes of Sucrose and Glucose Contents in Adherent Plaque of Plaque-Susceptible Rat [PDF]

, 1982
P(論文)This study was performed to measure sucrose and glucose contents in the adherent plaque of Plaque-Susceptible Rats(SUS). The rats were bred at Higashi Nippon Gakuen Univ. and at 5 weeks of age, fed a commercial powder diet.
金子, 久幸, 20394, 34595, 34594, 34593, 北村, 眞弓, 佐々木, 奈津子, 井藤, 信義   +7 more
core  

Ketogenic diet fails to mitigate seizures and neuroinflammatory responses in a mouse model of virus‐induced epilepsy

Epilepsia, EarlyView.
Abstract Objective The ketogenic diet (KD) is a high‐fat, low‐carbohydrate intervention widely used to treat drug‐resistant epilepsy, thought to reduce seizures through a combination of metabolic, neuronal, and microbiota‐dependent mechanisms. Additionally, recent studies suggest that the anticonvulsant effects of KD require the gut microbiota, with ...
Casey H. Meili, Kaitlyn Allen, Daniel J. Doty, Sofia Del Fiol, Ana Beatriz DePaula‐Silva   +4 more
wiley   +1 more source

Evaluation of the Ratio of Spot Tests and Plaque-Forming Activity Tests of Bacteriophages of Prevalent Pathogens

Эпидемиология и вакцинопрофилактика
Relevance. Obtaining clean lysis spots, with tolerable presence of individual colonies of secondary growth, in spot tests is a criterion for assessing the effectiveness of therapeutic bacteriophages.
I. M. Pchelin, D. V. Azarov, V. A. Dedik, D. A. Kushnirenko, B. I. Aslanov, A. E. Goncharov, D. A. Lioznov   +6 more
doaj   +1 more source

Confirmation of the inhibitory effect against viral growth by plaque assay.

, 2014
(A) Representative plaque assay is shown (6-well plate). (B) Quantitation of plaque forming units (PFU) is shown. Plaque formations with various concentrations of HK/Frag.10 and WSN/PB2 (from 0 to 2.0 µg/well) are expressed as a % relative to the plaque ...
Yusaku Uemura (668258), Takahito Kashiwagi (331245), Yoshihiro Imamura (668259), Yoko Nakazono (331242), Nobuyuki Hamada (237206), Koyu Hara (331244), Hiroshi Watanabe (81742)   +6 more
core   +1 more source

Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma

Equine Veterinary Journal, EarlyView.
Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source