Results 241 to 250 of about 6,612,528 (280)
Some of the next articles are maybe not open access.
Modulation of mitochondria by viral proteins
Life Sciences, 2023Mitochondria are dynamic cellular organelles with diverse functions including energy production, calcium homeostasis, apoptosis, host innate immune signaling, and disease progression. Several viral proteins specifically target mitochondria to subvert host defense as mitochondria stand out as the most suitable target for the invading viruses.
Reshu, Saxena +5 more
openaire +2 more sources
Trafficking of Viral Membrane Proteins
2005Many viruses express membrane proteins. For enveloped viruses in particular, membrane proteins are frequently structural components of the virus that mediate the essential tasks of receptor recognition and membrane fusion. The functional activities of these proteins require that they are sorted correctly in infected cells.
Rahel Byland, Mark Marsh
openaire +3 more sources
Viral chemokine-binding proteins
Journal of Leukocyte Biology, 2002AbstractThe chemokines are a large family of small signaling proteins that bind to G-protein-coupled receptors (GPCRs) on target cells and mediate the directional migration of immune cells into sites of infection or inflammation. The large DNA viruses, particularly the poxviruses and herpesviruses, have evolved several mechanisms to corrupt the normal ...
Grant McFadden, Bruce T. Seet
openaire +3 more sources
Synthesis of Tacaribe viral proteins
Virology, 1979Abstract The synthesis of Tacaribe virus-specific proteins in infected BHK-21 cells has been analyzed by polyacrylamide slab gel electrophoresis and fluorography. The two major structural polypeptides of the virion were observed above the host cell background by pulse labeling with amino acid or sugar precursors.
Richard W. Compans +2 more
openaire +3 more sources
1995
Since the discovery of the human immunodeficiency viruses types 1 (HIV-1) and 2 (HIV-2) as the causative agents of acquired immunodeficiency syndrome (AIDS) (Barre-Sinoussi et al. 1983; Clavel et al. 1987; Papovic et al. 1984) and the isolation of related lentiviruses from several species of Old World monkeys, much has been learned about their biology ...
openaire +3 more sources
Since the discovery of the human immunodeficiency viruses types 1 (HIV-1) and 2 (HIV-2) as the causative agents of acquired immunodeficiency syndrome (AIDS) (Barre-Sinoussi et al. 1983; Clavel et al. 1987; Papovic et al. 1984) and the isolation of related lentiviruses from several species of Old World monkeys, much has been learned about their biology ...
openaire +3 more sources
Myristoylation of viral and bacterial proteins
Trends in Microbiology, 2004Abstract Myristoylation, the N-terminal attachment of a myristoyl lipid anchor to a glycine residue, can reversibly direct protein–membrane and protein–protein interactions. Apart from two entomopoxviruses, viruses and bacteria usually lack the enzyme N-myristoyltransferase (NMT) that is required for this modification, and their proteins are ...
Frank Eisenhaber, Sebastian Maurer-Stroh
openaire +3 more sources
Identification of Immunoreactive Viral Proteins
2003Several diagnostic tools are available for the identification of acute and latent viral infections. Although newly developed nucleic acid amplification methods, such as the polymerase chain reaction (PCR), have proved to be very useful diagnostic procedures, conventional methods, such as cell culture and serology, still play an important role in viral ...
Bodo Plachter +2 more
openaire +3 more sources
Vaccination with Purified Viral Proteins [PDF]
, 1972 Inactivated viral vaccines currently in use consist, in most cases, of rather impure suspensions of virus particles and soluble antigens. It has been demonstrated that not all antigens of a given virus are required to induce antibody responses leading to protection.
openaire +2 more sources
Viral and Non-Viral Approaches for Transient Delivery of mRNA and Proteins
Current Gene Therapy, 2011The transient delivery of gene products (RNA or proteins) is not a biotechnological invention but rather an evolutionarily conserved process underlying and regulating a variety of biological functions. On the basis of insights into the underlying mechanisms, several viral and cell-based approaches have been developed for the delivery of RNA or proteins.
Axel Schambach +4 more
openaire +2 more sources
The Viral Tyrosine Protein Kinases
1986The acutely transforming retroviruses have revealed the existence of more than twenty different genes with oncogenic potential. Seven of these — src, abl, yes, erbB, fps (fes), fgr, fms, and ros — encode proteins with intrinsic tyrosine protein kinase activity.
openaire +3 more sources