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Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection

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VIRAL TRANSACTIVATING PROTEINS

Annual Review of Genetics, 1997
▪ Abstract  Many viruses utilize the cellular transcription apparatus to express their genomes, and they encode transcriptional regulatory proteins that modulate the process. Here we review the current understanding of three viral regulatory proteins.
J, Flint, T, Shenk
openaire   +2 more sources

Structural Disorder in Viral Proteins

Chemical Reviews, 2014
Xue, Bin   +6 more
openaire   +5 more sources

Viral complement regulatory proteins

Immunopharmacology, 1999
The inactivation of complement provides cells and tissues critical protection from complement-mediated attack and decreases the associated recruitment of other inflammatory mediators. In an attempt to evade the host immune response, viruses have evolved two mechanisms to acquire complement regulatory proteins.
A M, Rosengard, J M, Ahearn
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Viral chemokine-binding proteins

Journal of Leukocyte Biology, 2002
AbstractThe chemokines are a large family of small signaling proteins that bind to G-protein-coupled receptors (GPCRs) on target cells and mediate the directional migration of immune cells into sites of infection or inflammation. The large DNA viruses, particularly the poxviruses and herpesviruses, have evolved several mechanisms to corrupt the normal ...
Bruce T, Seet, Grant, McFadden
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Relationship between viral RNA and viral protein synthesis

Virology, 1962
Abstract Low concentrations of p-fluorophenylalanine (5–10 μg/ml) inhibit the maturation of Western equine encephalomyelitis and poliomyelitis viruses. Much higher concentrations are required (125 μg/ml) to inhibit the synthesis of the respective infectious RNA. By means of fluorescent antibodies against poliovirus, it was found that the formation of
E, WECKER, K, HUMMELER, O, GOETZ
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Viral protein kinases and protein phosphatases

Pharmacology & Therapeutics, 1993
Certain large DNA viruses (e.g. herpesviruses and poxviruses) encode proteins related to cellular protein-serine/threonine kinases, and Hepatitis B virus and vesicular stomatitis virus may encode structurally different protein kinases. Other viruses activate cellular protein kinases, e.g. interferon-induced eukaryotic initiation factor-2 kinase, growth
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Virally Encoded Chemokine Binding Proteins

Mini-Reviews in Medicinal Chemistry, 2005
Virus-encoded immune evasion mechanisms provide information on viral pathogenesis and offer a unique opportunity to identify new strategies of immune modulation. Secreted proteins that bind a broad range of chemokines have been identified in recent years in poxviruses and herpesviruses.
Louise M C, Webb, Antonio, Alcami
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Viral Protein X

1995
Since the discovery of the human immunodeficiency viruses types 1 (HIV-1) and 2 (HIV-2) as the causative agents of acquired immunodeficiency syndrome (AIDS) (Barre-Sinoussi et al. 1983; Clavel et al. 1987; Papovic et al. 1984) and the isolation of related lentiviruses from several species of Old World monkeys, much has been learned about their biology ...
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