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2016
Cancer immunotherapy is a rapidly evolving field and the search for appropriate targets to come up with robust immunotherapeutic strategies for the treatment of cancers is a continuous process. Viral-like proteins are known to have an important role in the oncogenesis and their potential as cancer therapeutic targets is yet to be completely explored ...
Lavakumar Karyampudi, Keith L. Knutson
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Cancer immunotherapy is a rapidly evolving field and the search for appropriate targets to come up with robust immunotherapeutic strategies for the treatment of cancers is a continuous process. Viral-like proteins are known to have an important role in the oncogenesis and their potential as cancer therapeutic targets is yet to be completely explored ...
Lavakumar Karyampudi, Keith L. Knutson
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Identification of Immunoreactive Viral Proteins
2003Several diagnostic tools are available for the identification of acute and latent viral infections. Although newly developed nucleic acid amplification methods, such as the polymerase chain reaction (PCR), have proved to be very useful diagnostic procedures, conventional methods, such as cell culture and serology, still play an important role in viral ...
W, Hinderer, B, Plachter, R, Vornhagen
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Trafficking of Viral Membrane Proteins
2005Many viruses express membrane proteins. For enveloped viruses in particular, membrane proteins are frequently structural components of the virus that mediate the essential tasks of receptor recognition and membrane fusion. The functional activities of these proteins require that they are sorted correctly in infected cells.
R, Byland, M, Marsh
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Synthesis of Tacaribe viral proteins
Virology, 1979Abstract The synthesis of Tacaribe virus-specific proteins in infected BHK-21 cells has been analyzed by polyacrylamide slab gel electrophoresis and fluorography. The two major structural polypeptides of the virion were observed above the host cell background by pulse labeling with amino acid or sugar precursors.
F, Saleh, G P, Gard, R W, Compans
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Intercellular Transport of Viral Proteins
Viruses are vehicles to exchange genetic information and proteins between cells and organisms by infecting their target cells either cell-free, or depending on cell-cell contacts. Several viruses like certain retroviruses or herpesviruses transmit by both mechanisms.Florian, Simon, Andrea K, Thoma-Kress
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The Viral Tyrosine Protein Kinases
1986The acutely transforming retroviruses have revealed the existence of more than twenty different genes with oncogenic potential. Seven of these — src, abl, yes, erbB, fps (fes), fgr, fms, and ros — encode proteins with intrinsic tyrosine protein kinase activity.
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Vaccination with Purified Viral Proteins
1972Inactivated viral vaccines currently in use consist, in most cases, of rather impure suspensions of virus particles and soluble antigens. It has been demonstrated that not all antigens of a given virus are required to induce antibody responses leading to protection.
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Viral channel-forming proteins.
International review of cell and molecular biology, 2009Channel-forming proteins are found in a number of viral genomes. In some cases, their role in the viral life cycle is well understood, in some cases it needs still to be elucidated. A common theme is that their mode of action involves a change of electrochemical or proton gradient across the lipid membrane which modulates the viral or cellular activity.
Wolfgang B, Fischer, Jens, Krüger
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Antibodies to combat viral infections: development strategies and progress
Nature Reviews Drug Discovery, 2022Giuseppe Pantaleo +2 more
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