Results 231 to 240 of about 438,262 (317)

A conserved RNA structure at the capsid-coding sequence of Zika virus genome is required for viral replication in a host-dependent manner. [PDF]

J Virol
Costa Navarro GS, Pallarés HM, González López Ledesma MM, de Borba L, Mazzolenis R, Gamarnik AV.   +5 more
europepmc   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Monkeypox virus induces ferroptosis to facilitate viral replication and promotes inflammatory responses. [PDF]

Emerg Microbes Infect
Chuai X, Wang Y, Wang C, Ye T, Shen X, Zhou J, Zhang K, Zhao B, Wu Y, Li W, Cai Z, Chiu S.   +11 more
europepmc   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Zika Virus Reprograms Microglial Mitochondrial Metabolism to Support Immune Activation and Viral Replication: Omega-3 DHA Counteracts Neuroinflammation and Viral Persistence. [PDF]

Mol Neurobiol
Braz-de-Melo HA, Lago FG, Corrêa R, Santos IO, Bellozi PMQ, Almeida RDN, Fontes W, Castro MS, Martins AMA, de Oliveira RM, Rossi NMS, Pasquarelli-do-Nascimento G, Gouvea AL, Prado PS, de Bem AF, Báo SN, Ribeiro BM, Rehen SK, Williams TCR, Kobinger GP, Magalhães KG.   +20 more
europepmc   +1 more source

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

Deciphering pUL10's mastery in duck plague virus virulence: dual coordination of host immunity and viral replication. [PDF]

Poult Sci
Li C, Wang M, Cheng A.
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Regulation of viral replication by host restriction factors. [PDF]

Front Immunol
Lin Y, Zhu Y, Jing L, Lei X, Xie Z.
europepmc   +1 more source

Referee report. For: Identification of diverse defense mechanisms in trout red blood cells in response to VHSV halted viral replication [version 1; referees: 1 approved with reservations]

, 2017
Aleksei Krasnov
openalex   +1 more source