Results 231 to 240 of about 428,951 (317)
Newcastle disease virus induces degradation of folliculin to regulate host cell energy metabolism and facilitate viral replication. [PDF]
Yang M +8 more
europepmc +1 more source
Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma +10 more
wiley +1 more source
Interaction of Newcastle disease virus V protein with EFTUD2 modulates MDA5 pathway to suppress viral replication. [PDF]
Han Y, Zhang F, Zhou Z, Huang Y, Chen R.
europepmc +1 more source
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source
Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti-Alphavirus Therapies. [PDF]
Wang S, Mahalingam S, Merits A.
europepmc +1 more source
PRDM16 Reduces Cellular Senescence by Upregulating GSTM1
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan +7 more
wiley +1 more source
Backsplicing of the HIV-1 transcript generates multiple circRNAs to promote viral replication. [PDF]
Mauer C, Paz S, Caputi M.
europepmc +1 more source

