Results 231 to 240 of about 617,233 (366)

Regulation of viral replication by host restriction factors. [PDF]

Front Immunol
Lin Y, Zhu Y, Jing L, Lei X, Xie Z.
europepmc   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Newcastle disease virus induces degradation of folliculin to regulate host cell energy metabolism and facilitate viral replication. [PDF]

Poult Sci
Yang M, Kan X, Li X, Sun Y, Liao Y, Qiu X, Tan L, Song C, Ding C.   +8 more
europepmc   +1 more source

Intracellular Formation of Synthetic Peptide Nanostructures Causes Mitochondrial Disruption and Cell Death in Tumor Spheroids

Advanced Science, EarlyView.
Synthetic peptide nanostructures, formed within cancer cells in response to glutathione, lead to mitochondrial dysfunction and cell death. The nanostructures significantly damage mitochondrial networks, impair cellular respiration, and induce cell death in both 2D cultures and 3D tumor spheroids.
Sarah Chagri, Konrad Maxeiner, Maria J. S. A. Silva, Lisa Förch, Julian Link, Patrick Roth, Raphael Meyer, Jana Fetzer, Anke Kaltbeitzel, Ingo Lieberwirth, Katharina Landfester, Manfred Wagner, David Y.W. Ng, Tanja Weil   +13 more
wiley   +1 more source

Regulatory function of simian virus 40 DNA replication for late viral gene expression.

, 1977
A. Graessmann, M. Graessmann, Christoph Mueller   +2 more
openalex   +1 more source

Host cytoskeleton and membrane network remodeling in the regulation of viral replication. [PDF]

Biophys Rep
Gao X, Chen X, Yu L, Zhao S, Jiu Y.
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Detecting the ability of viral, bacterial and eukaryotic replication proteins to track along DNA. [PDF]

, 1994
Rachel L. Tinker, George A. Kassavetis, E. Peter Geiduschek   +2 more
openalex   +1 more source

Association Between Viral Replication Activity and Postoperative Recurrence of HBV-Related Hepatocellular Carcinoma. [PDF]

Aliment Pharmacol Ther
Heo S, Yang J, Park J, Hui RW, Song BG, Song IH, Yoon YI, Cheung TT, Chung SW, Choi J, Lee D, Shim JH, Kim KM, Lim YS, Lee HC, Seto WK, Lee JH, Choi WM.   +17 more
europepmc   +1 more source

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

Advanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li, Justin Torok, Shujing Zhang, Jessica Ding, Ning Wang, Courtney Lau, Shruti Kulkarni, Chaitali Anand, Julie Tran, Michael Cheng, Claire Lo, Binbin Lu, Yanzi Sun, Robert Damoiseaux, Xia Yang, Ashish Raj, Chao Peng   +16 more
wiley   +1 more source