Results 151 to 160 of about 84,140 (293)

KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir. [PDF]

open access: yesCell Rep Med, 2023
Astorga-Gamaza A   +16 more
europepmc   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

open access: yesExploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen   +8 more
wiley   +1 more source

Recent advances in multifunctional soft robots: A materials–structures–systems co‐design perspective for synergistic integration

open access: yesFlexMat, EarlyView.
Abstract Soft robots, engineered from highly compliant materials, offer superior adaptability and safety in unstructured environments compared to their rigid counterparts. Recent advancements, fueled by bio‐inspiration and material programmability, have led to the rapid co‐evolution of their core modules: actuation, sensing, protection, energy, and ...
Qiulei Liu   +3 more
wiley   +1 more source

Anti-HIV therapy: pipeline approaches and future directions

open access: yes, 2011
Human immunodeficiency virus (HIV), with about 30 million deaths and double infections (in developing countries), is an open challenge today for global scientists.
Lavkush Dwivedi, Mansi Shrivastava
core   +1 more source

Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial. [PDF]

open access: yesCells, 2023
Mboumba Bouassa RS   +19 more
europepmc   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun   +11 more
wiley   +1 more source

Mathematical and computational model for the study of evolution and viral adaptation with reservoir

open access: yes, 2017
Resumo A teoria da mutagênese letal prevê que populações de vírus de RNA poderiam se extintas pela redução de sua capacidade replicativa média (número médio de progênies por célula infectada), desencadeada pela elevação das taxas de mutação deletérias ...
Gorzoni, Bruno Zanardo [UNIFESP]
core  

HPV‐Related Cancers in Solid Organ Transplant Recipients: A Nationwide Danish Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
Solid organ transplant recipients (SOTRs) face chronic immunosuppression, leaving them susceptible to viral infections. Of particular concern is persistent infection with human papillomavirus (HPV), which presents a significant cancer risk. This nationwide Danish cohort study estimated cancer risk in SOTRs using health registry data.
Signe Timm   +7 more
wiley   +1 more source

Evolving Strategies to Eliminate the CD4 T Cells HIV Viral Reservoir via CAR T Cell Immunotherapy. [PDF]

open access: yesFront Immunol, 2022
York J   +5 more
europepmc   +1 more source

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

open access: yesiMetaMed, EarlyView.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen   +4 more
wiley   +1 more source

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