Results 241 to 250 of about 24,194,770 (306)

Preliminary Screening for Selected Viral Pathogens in Red Fox Carcasses from Pisa Province, Italy. [PDF]

Pathogens
Forzan M, Banducci G, Mazzei M, Soares Filipe J, Verin R, Senese M, Cingottini D, Sgorbini M, Parisi F.   +8 more
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Molecular characterization of a novel partitivirus harboring an additional third dsRNA segment from Trichoderma harzianum. [PDF]

Arch Virol
Kim JE, Chun J, Ko YH, Kim DH.
europepmc   +1 more source

Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7

Advanced Science, EarlyView.
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim, Gaeun Lee, Saemin An, Hanseul Park, Hongwon Kim, Jisung Kim, Soi Kang, Sumin Kim, Daeyeol Kwon, Jeonghyun Park, Yerim Hwang, Seonghun Kim, Xiuwen Yuan, Jaehoon Jeong, Hamin Lee, Hui Kwon Kim, Jongpil Kim   +16 more
wiley   +1 more source

Identification of Partitivirus-like RdRPs in the <i>Brevipalpus yothersi</i> Genome Supports Viral-to-Arthropod Horizontal Gene Transfer. [PDF]

Viruses
Corrêa BA, Medinilha Pancher T, Calandriello Calio D, Tassi AD, Pereira LR, Carrillo D, Harakava R, Novelli VM, Kitajima EW, Ramos-González PL, Freitas-Astúa J, Gonzalez-Ibeas D.   +11 more
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

The spatial structure of dengue transmission in Kamphaeng Phet Thailand. [PDF]

PLoS Negl Trop Dis
Ooi SH, Huang AT, Kaewhiran S, Farmer A, Buddhari D, Li T, Gandhi J, Pollio AR, Hang J, Conte MA, Cummings DAT, Anderson K, Salje H.   +12 more
europepmc   +1 more source

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

Advanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song, Zilu Zhu, Yujun Deng, Yujie Song, Hui Li, Junjun Ni, Zhenzhen Quan, Yan Yan, Hong Qing   +8 more
wiley   +1 more source

Comprehensive Analysis of Insertions in BVDV and Implications for Non-Homologous Recombination Mechanisms. [PDF]

Viruses
Perelygin F, Aleshina Y, Chistiakova E, Orlov A, Lukashev A.   +4 more
europepmc   +1 more source