Results 261 to 270 of about 24,194,770 (306)

Ultra-deep sequencing for the analysis of viral populations

Current Opinion in Virology, 2011
Next-generation sequencing allows for cost-effective probing of virus populations at an unprecedented level of detail. The massively parallel sequencing approach can detect low-frequency mutations and it provides a snapshot of the entire virus population.
Beerenwinkel N, Zagordi O
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Signature Pattern Analysis: A Method for Assessing Viral Sequence Relatedness

AIDS Research and Human Retroviruses, 1992
Signature pattern analysis identifies particular sites in amino acid or nucleic acid alignments of variable sequences that are distinctly representative of a query set of sequences relative to a background set. We explore the merits of using signature patterns for analysis of HIV-1 (human immunodeficiency virus type 1) sequences in cases of ...
B, Korber, G, Myers
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Analysis of viral sequence variation by PCR

1993
Abstract Sequence analysis has played a fundamental part in virological research since methods for the determination of nucleotide sequences were developed in the late 1970s (1, 2). However, these techniques require relatively large amounts of template DNA which are often obtainable only by virus culture in vitro and DNA cloning.
Chan, Shiu-Wan, Simmonds, Peter
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Markov analysis of viral DNA/RNA sequences

Journal of Theoretical Biology, 1980
Abstract This work applies a previously published method for determining the order of a Markov chain to the DNA/RNA sequences of φX174, SV40 and MS2. In the first two cases rather long-range order is found—third and second order respectively—but zero order is the appropriate model for MS2.
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