Results 271 to 280 of about 24,194,770 (306)

Structure based sequence analysis of viral and cellular protein assemblies

Journal of Structural Biology, 2016
It is well accepted that, in general, protein structural similarity is strongly related to the amino acid sequence identity. To analyze in great detail the correlation, distribution and variation levels of conserved residues in the protein structure, we analyzed all available high-resolution structural data of 5245 cellular complex-forming proteins and
Daniel J, Montiel-García, Ranjan V, Mannige, Vijay S, Reddy, Mauricio, Carrillo-Tripp   +3 more
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Organization of type C viral DNA sequences endogenous to baboons: analysis with cloned viral DNA

Journal of Virology, 1982
Unintegrated linear and circular forms of baboon endogenous type C virus M7 DNA were prepared from M7-infected cells by chromatography on hydroxyapatite columns, and the circular DNAs were purified in cesium chloride-ethidium bromide equilibrium density gradients. The circular DNAs were linearized by digestion with EcoRI, which had a unique site on the
N, Battula, G L, Hager, G J, Todaro
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Algorithms for analysis of next-generation viral sequencing data

2021
RNA viruses mutate at extremely high rates, forming an intra-host viral population of closely related variants, which allows them to evade the host’s immune system and makes them particularly dangerous. Viral outbreaks pose a significant threat for public health.
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Sequencing and comparative analysis of a pig bovine viral diarrhea virus genome

Virus Research, 2006
In present study, we report the first complete genomic sequence of pig bovine viral diarrhea (BVD) virus, that of strain ZM-95, which is 12,220 nucleotides long and contains short 5' and 3' non-coding regions and one open reading frame encoding a large polyprotein with 28 potential N-glycosylation sites (Asn-X-Ser or Asn-X-Thr).
Xingran, Xu, Qingchan, Zhang, Xinglong, Yu, Long, Liang, Chang, Xiao, Hua, Xiang, Changchun, Tu   +6 more
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Partial Sequence Analysis of the Hepatitis C Viral Genome in Singapore Patients

Biochemical and Biophysical Research Communications, 1994
The distribution of hepatitis C viral (HCV) genotypes in Singapore has not been previously determined. We studied the sera of 40 Singapore patients which were PCR-positive for HCV. The HCV genotypes were determined by direct sequencing of amplified sequences of the 5' non-coding region, after reverse transcription. Of the 40 samples, 35/40 (87.5%) were
LEE, ASG, NG, KY, CHEE, MKL, VATHSALA, A, CHOONG, HL, NG, HS, OON, CJ   +6 more
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Performance assessment of the Illumina massively parallel sequencing platform for deep sequencing analysis of viral minority variants

Journal of Virological Methods, 2015
Massively parallel sequencing (MPS) technology has opened new avenues to study viral dynamics and treatment-induced resistance mechanisms of infections such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Whereas the Roche/454 platform has been used widely for the detection of low-frequent drug resistant variants, more recently ...
Kim, Thys, Peter, Verhasselt, Joke, Reumers, Bie M P, Verbist, Bart, Maes, Jeroen, Aerssens   +5 more
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Visitor, An Informatic Pipeline for Analysis of Viral siRNA Sequencing Datasets

2011
High-throughput sequencing emerged as a powerful approach to characterize siRNA populations -generated by hosts in response to viral infections. Here we described an informatic pipeline visitor to analyze in-house large sequencing datasets generated from Illumina sequencing of Drosophila small RNA libraries. The visitor perl script is designed to treat
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Viral Sequence Database Manager (VSDBM): A Distributed Framework for Viral Genomic Analysis and Epitope Mapping

Lecture Notes in Computer Science
Tiago Feitosa Mota, Eduardo Rocha Fukutani   +1 more
exaly   +2 more sources

Sequence analysis and characterisation of virally induced viperin in the saltwater crocodile (Crocodylus porosus)

Developmental & Comparative Immunology, 2015
A number of pathogens have been detected in crocodiles, however little is known about their ability to control these pathogens. The interferon stimulated gene (ISG), viperin, has gained attention recently as an important host protein involved in multiple arms of the immune response.
Milic, N., Davis, S., Carr, J., Isberg, S., Beard, M., Helbig, K.   +5 more
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[Computer analysis of viral genomic structural organization by sequence scanning].

Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 2003
The results of testing the author's computer program for viral genomic sequences scanning (program Scangene) are presented in the paper. It has been shown on model nucleotide sequences as well as on genomic and predicted protein sequences of tobamo-, potex- and bromoviruses that the program is suitable for the quick revealing of identical, similar and ...
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