Results 11 to 20 of about 363,177 (305)
Structural characterization of viral fusion proteins [PDF]
Current Biology, 1995 Infection by enveloped viruses is initiated by the fusion of viral and cellular membranes. In many cases, the viral membrane proteins that mediate fusion must undergo conformational changes to become active. Influenza hemagglutinin, for example, is activated by a dramatic conformational rearrangement, triggered by the low pH of the intracellular ...
Hughson, Frederick M.
openaire +4 more sources
New Biophysical Approaches Reveal the Dynamics and Mechanics of Type I Viral Fusion Machinery and Their Interplay with Membranes [PDF]
Viruses, 2020 Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
doaj +2 more sources
Roles of the Non-Structural Proteins of Influenza A Virus [PDF]
Pathogens, 2020 Influenza A virus (IAV) is a segmented, negative single-stranded RNA virus that causes seasonal epidemics and has a potential for pandemics. Several viral proteins are not packed in the IAV viral particle and only expressed in the infected host cells ...
Wenzhuo Hao, Lingyan Wang, Shitao Li
doaj +2 more sources
Structural Virology: The Key Determinants in Development of Antiviral Therapeutics [PDF]
VirusesStructural virology has emerged as the foundation for the development of effective antiviral therapeutics. It is pivotal in providing crucial insights into the three-dimensional frame of viruses and viral proteins at atomic-level or near-atomic-level ...
Tanuj Handa +6 more
doaj +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Dengue is emerging as one of the most prevalent mosquito-borne viral diseases of humans. The 11kb RNA genome of the dengue virus encodes three structural proteins (envelope, pre-membrane, capsid) and seven non-structural proteins (NS1, NS2A, NS2B, NS3 ...
Priya Bhatnagar +6 more
doaj +1 more source
Visualization and analysis of hepatitis C virus structural proteins at lipid droplets by super-resolution microscopy. [PDF]
PLoS ONE, 2014 Cytosolic lipid droplets are central organelles in the Hepatitis C Virus (HCV) life cycle. The viral capsid protein core localizes to lipid droplets and initiates the production of viral particles at lipid droplet-associated ER membranes. Core is thought
Dennis Eggert +3 more
doaj +1 more source
Genes of SARS-CoV-2 and emerging variants [PDF]
Microbiology Australia, 2021 The pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is distinctly different from outbreaks caused by other coronaviruses: SARS-CoV andMiddle East respiratory syndrome coronavirus (MERS-CoV).
Ian Macreadie, Sudip Dhakal
doaj
An Overview of Spike Surface Glycoprotein in Severe Acute Respiratory Syndrome–Coronavirus
Frontiers in Molecular Biosciences, 2021 The novel coronavirus originated in December 2019 in Hubei, China. This contagious disease named as COVID-19 resulted in a massive expansion within 6 months by spreading to more than 213 countries.
Muthu Kumaradoss Kathiravan +5 more
doaj +1 more source
Viruses, 2018 Chikungunya virus (CHIKV) has re-emerged as one of the many medically important arboviruses that have spread rampantly across the world in the past decade.
Kai Zhi Wong, Justin Jang Hann Chu
doaj +1 more source
Вопросы вирусологии, 2023 Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva +3 more
doaj +1 more source