Viral suppression of RNA silencing in plants
Molecular Plant Pathology, 2004 SUMMARY RNA silencing is a conserved eukaryotic pathway involved in suppression of gene expression via sequence‐specific interactions that are mediated by nt 21–24‐long RNA molecules. In plants, cell‐autonomous and noncell‐autonomous steps of RNA silencing form the basis of an elaborate immune system that is activated by, and targeted
Guillaume, Moissiard, Olivier, Voinnet
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Suppression of Viral RNA Recombination by a Host Exoribonuclease [PDF]
Journal of Virology, 2006 ABSTRACT RNA viruses of humans, animals, and plants evolve rapidly due to mutations and RNA recombination. A previous genome-wide screen in Saccharomyces cerevisiae , a model host, identified five host genes, including XRN1 , encoding a 5′-3′ exoribonuclease, whose absence led to an
Chi-Ping, Cheng +2 more
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, 2023 Eshetu Erjino, Ermias Abera, Lire Lemma Tirore Department of Public Health, College of Medicine and Health Sciences, Wachemo University, Hossana, Sothern EthiopiaCorrespondence: Lire Lemma Tirore, Email ganetlemma@gmail.comBackground: Unsuppressed viral ...
Lemma Tirore L, Erjino E, Abera E
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HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers [PDF]
, 2009 Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment ...
C. J. Brumme +21 more
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Viral load suppression cascade.
, 2023 Viral load suppression cascade.
Tinei Shamu (4532530) +12 more
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Structural and functional studies of novel mechanisms of Lassa fever virus nucleoprotein in immune suppression, viral RNA transcription and replication [PDF]
, 2013 Lassa fever virus is one of the most dangerous viruses of arenaviridae family, causing more than 500,000 infections per year in Africa. The fatality rate for hospitalized patients is as high as 20%.
Qi, Xiaoxuan
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Reduction in time to viral suppression among persons living with HIV in Jamaica between 2017-2019.
PLOS Global Public HealthIntroductionHIV viral suppression is important for effective treatment and for reducing new infections. In 2019, only 66% of persons on antiretroviral treatment (ART) in Jamaica were virally suppressed.
Anya Cushnie +3 more
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Viral DNAemia and Immune Suppression in Pediatric Sepsis [PDF]
Pediatric Critical Care Medicine, 2018 Objectives: Demonstrate that DNA viremia is common in pediatric sepsis and quantitate its associations with host immune function and secondary infection risk. Design: Retrospective analysis of a prospective cohort study.
Sam, Davila +7 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Time to undetectable viral load after highly active antiretroviral therapy initiation among HIV-infected pregnant women [PDF]
, 2007 Background. There have been no clinical trials in resource-rich regions that have addressed the question of which highly active antiretroviral therapy (HAART) regimens are more effective for optimal viral response in antiretroviral-naive, human ...
Patel, D, European Collaborative Study
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