Results 191 to 200 of about 614,007 (276)
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.In this study, a mouse monoclonal and rabbit polyclonal antibodies were used as capture and detection antibodies, respectively, to develop a DAS‐ELISA that can be used for viral antigen detection. ABSTRACT Objectives Double‐antibody sandwich enzyme‐linked immunosorbent assay (DAS‐ELISA) is a simple and accurate method for detecting viral pathogens ...
Bo Dong +7 more
wiley +1 more source
Feline bocavirus-1 associated with outbreaks of hemorrhagic enteritis in household cats: potential first evidence of a pathological role, viral tropism and natural genetic recombination. [PDF]
Sci Rep, 2019 Piewbang C +3 more
europepmc +1 more source
Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)
Journal of Fish Diseases, Volume 49, Issue 11, November 2026.ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon +12 more
wiley +1 more source
Journal of Fish Diseases, Volume 49, Issue 11, November 2026.ABSTRACT Large‐scale double‐digest RAD sequencing (ddRADseq) datasets generated for genotyping are increasingly available in aquaculture, yet their unmapped reads remain largely unexplored for pathogen surveillance. Here, we evaluated the utility and limitations of repurposing unmapped ddRADseq reads to examine pathogen‐associated and disease ...
Nguyen Thanh Vu +11 more
wiley +1 more source
Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano +3 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, Volume 13, Issue 55, 5 October 2026.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang +9 more
wiley +1 more source
Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.Pathogenesis of bacterial diseases in Nile tilapia and anti‐bacterial mechanisms. ABSTRACT Nile tilapia (Oreochromis niloticus) is among the most widely farmed fish globally that plays a major role in ensuring food security in many low‐ and middle‐income countries.
Catherine Agoe +8 more
wiley +1 more source