Results 251 to 260 of about 614,007 (276)

Viral tropism and pathology associated with viral hemorrhagic septicemia in larval and juvenile Pacific herring

Veterinary Microbiology, 2012
Viral hemorrhagic septicemia virus (VHSV) genotype IVa causes mass mortality in wild Pacific herring, a species of economic value, in the Northeast Pacific Ocean. Young of the year herring are particularly susceptible and can be carriers of the virus.
Jan Lovy, P K Hershberger, T R Meyers
exaly   +3 more sources

Molecular Analysis of Receptor Binding and Viral Tropism

1991
Human Immunodeficiency Virus (HIV), the etiologic agent of AIDS (Acquired Immunodeficiency Syndrome) displays a selective tropism for CD4-positive lymphocytes and for CD4-positive cells of the mononuclear-phagocyte lineage. Infection of target cells is initiated by the specific interaction of HIV envelope protein gpl20 and the CD4 molecule on the cell ...
A, Cordonnier, L, Montagnier
openaire   +2 more sources

Viral proteomics: A promising approach for understanding JC virus tropism

PROTEOMICS, 2006
AbstractThe human polyomavirus JC virus (JCV) is responsible for the CNS demyelination observed in cases of progressive multifocal leukoencephalopathy. The JCV regulatory region (promoter) is a hypervariable, noncoding, nucleotide sequence positioned between the early and late protein‐coding regions in the viral genome.
Veerasamy, Ravichandran, Eugene O, Major
openaire   +2 more sources

Viral Genes and Tissue Tropism

1984
A major feature of viral infections is their localization in specific cells and tissues [1]. This specific localization of different viruses into different tissues, as well as to different cells within those tissues, results in distinct patterns of infectious diseases [2]. Recent studies with the mammalian reoviruses and their infection of newborn mice
openaire   +1 more source

HIV-1 Coreceptors and Viral Tropism

1999
The past two years have witnessed the rapid merging of the HIV and chemokine-receptor fields, no doubt to the surprise of all involved (reviewed in refs. 1–4). It became evident soon after the discovery of CD4 as the primary receptor for HIV-1 that one or more additional cell-surface molecules (coreceptors) were required in conjunction with CD4 to ...
Robert W. Doms, John P. Moore
openaire   +1 more source

Perspectives on Cellular Receptors as Determinants of Viral Tropism

1988
Coxsackievirus (CV) infections of humans were recently reviewed1 and are also discussed elsewhere in this volume. These agents cause a wide variety of syndromes, including meningitis, pleurodynia, myositis, herpangina, myocarditis, pericarditis, pancreatitis, hepatitis, nephritis, orchitis, gastroenteritis, exanthems, acute respiratory disease, and ...
Richard L. Crowell, Burton J. Landau, Kuo-Hom Lee Hsu, Maggie Schultz   +3 more
openaire   +1 more source

Viral and Cellular Factors Influencing HIV Tropism

1991
Studies of the human immunodeficiency virus (HIV) have indicated that virus-infected cells are most likely the major source of infection, and any approach that kills only the virus would not control HIV infection (1). Early observations suggested that the CD4+ T helper lymphocyte was the major cell type infected by HIV (2).
openaire   +2 more sources

Heparan sulfate and viral tropism

Nature Medicine, 1997
T, Bergström, E, Trybala, D, Spillmann
openaire   +2 more sources

Viral determinants of JCV tropism

Journal of Neurovirology, 2004
GV Gee, WJ Atwood
openaire   +1 more source

[Methods for determining viral tropism: genotype and phenotype tests].

Enfermedades infecciosas y microbiologia clinica, 2009
The recent approval of the first CCR5 antagonist, Maraviroc (MVC, Celsentri), with specific antiviral activity against R5-tropic virus variants has generated the need for studies to determine the viral tropism in all those patient candidates for starting treatment with this new drug.
Mayte, Perez-Olmeda, Eva, Poveda
openaire   +1 more source