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Transmissible Viral Vaccines. [PDF]
Trends Microbiol, 2018 Genetic engineering now enables the design of live viral vaccines that are potentially transmissible. Some designs merely modify a single viral genome to improve on the age-old method of attenuation whereas other designs create chimeras of viral genomes.
Bull JJ, Smithson MW, Nuismer SL.
europepmc +4 more sources
Future perspectives on swine viral vaccines: where are we headed? [PDF]
Porcine Health Manag, 2021 Opriessnig T +3 more
europepmc +3 more sources
Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundViral vaccines have been proven significant in protecting us against viral diseases such as COVID-19. To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines and ...
Anthony Huffman +8 more
doaj +2 more sources
To Include or Occlude: Rational Engineering of HCV Vaccines for Humoral Immunity
Viruses, 2021 Direct-acting antiviral agents have proven highly effective at treating existing hepatitis C infections but despite their availability most countries will not reach the World Health Organization targets for elimination of HCV by 2030.
Felicia Schlotthauer +2 more
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Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines
Vaccines, 2022 New influenza strains are constantly emerging, causing seasonal epidemics and raising concerns to the risk of a new global pandemic. Since vaccination is an effective method to prevent the spread of the disease and reduce its severity, the development of
Zeyu Yang +10 more
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Vaccines, 2023 The administration of viral vectored vaccines remains one of the most effective ways to respond to the ongoing novel coronavirus disease 2019 (COVID-19) pandemic.
Zeyu Yang +5 more
doaj +1 more source
iScience, 2021 Summary: Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as well ...
Juanjie Tang +9 more
doaj +1 more source
Current Opinion in Immunology, 2022 Over the past two years, the SARS-CoV-2 pandemic has highlighted the impact that emerging pathogens can have on global health. The development of new and effective vaccine technologies is vital in the fight against such threats. Viral vectors are a relatively new vaccine platform that relies on recombinant viruses to deliver selected immunogens into ...
McCann, N +3 more
openaire +3 more sources
Vaccines, 2021 The ongoing COVID-19 pandemic drew global attention to infectious diseases, attracting numerous resources for development of pandemic preparedness plans and vaccine platforms—technologies with robust manufacturing processes that can quickly be pivoted to
Julia Puppin Chaves Fulber +7 more
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Open Life Sciences, 2022 In influenza vaccine development, Madin–Darby canine kidney (MDCK) cells provide multiple advantages, including large-scale production and egg independence. Several cell-based influenza vaccines have been approved worldwide.
Zhang Zhegang +19 more
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