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Transmissible Viral Vaccines [PDF]
Genetic engineering now enables the design of live viral vaccines that are potentially transmissible. Some designs merely modify a single viral genome to improve on the age-old method of attenuation whereas other designs create chimeras of viral genomes.
James J. Bull+2 more
openaire +4 more sources
Inactivated Viral Vaccines [PDF]
Inactivated vaccines have been used for over a century to induce protection against viral pathogens. This established approach of vaccine production is relatively straightforward to achieve and there is an augmented safety profile as compared to their live counterparts.
Barbara Petronella Sanders+2 more
openaire +2 more sources
Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase [PDF]
BackgroundViral vaccines have been proven significant in protecting us against viral diseases such as COVID-19. To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines and ...
Anthony Huffman+8 more
doaj +2 more sources
60 Years of viral vaccines [PDF]
Wahren B.
openaire +4 more sources
To Include or Occlude: Rational Engineering of HCV Vaccines for Humoral Immunity
Direct-acting antiviral agents have proven highly effective at treating existing hepatitis C infections but despite their availability most countries will not reach the World Health Organization targets for elimination of HCV by 2030.
Felicia Schlotthauer+2 more
doaj +1 more source
Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines
New influenza strains are constantly emerging, causing seasonal epidemics and raising concerns to the risk of a new global pandemic. Since vaccination is an effective method to prevent the spread of the disease and reduce its severity, the development of
Zeyu Yang+10 more
doaj +1 more source
The administration of viral vectored vaccines remains one of the most effective ways to respond to the ongoing novel coronavirus disease 2019 (COVID-19) pandemic.
Zeyu Yang+5 more
doaj +1 more source
The ongoing COVID-19 pandemic drew global attention to infectious diseases, attracting numerous resources for development of pandemic preparedness plans and vaccine platforms—technologies with robust manufacturing processes that can quickly be pivoted to
Julia Puppin Chaves Fulber+7 more
doaj +1 more source
Over the past two years, the SARS-CoV-2 pandemic has highlighted the impact that emerging pathogens can have on global health. The development of new and effective vaccine technologies is vital in the fight against such threats. Viral vectors are a relatively new vaccine platform that relies on recombinant viruses to deliver selected immunogens into ...
McCann, N+3 more
openaire +3 more sources
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8+ T Cell Responses, Enabling Faster Resolution of Influenza Disease [PDF]
Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of
Bogen, B+8 more
core +10 more sources