Results 21 to 30 of about 1,490,578 (344)

Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

open access: yesSignal Transduction and Targeted Therapy, 2023
Human diseases, particularly infectious diseases and cancers, pose unprecedented challenges to public health security and the global economy.
Shen Wang   +9 more
semanticscholar   +1 more source

SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions [PDF]

open access: goldViruses, 2020
The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus that impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic infections to mild respiratory symptoms to the lethal form of COVID-19 which is ...
Mohammed Uddin   +12 more
openalex   +2 more sources

Preclinical immunogenicity assessment of a cell-based inactivated whole-virion H5N1 influenza vaccine

open access: yesOpen Life Sciences, 2022
In influenza vaccine development, Madin–Darby canine kidney (MDCK) cells provide multiple advantages, including large-scale production and egg independence. Several cell-based influenza vaccines have been approved worldwide.
Zhang Zhegang   +19 more
doaj   +1 more source

Development and Scalable Production of Newcastle Disease Virus-Vectored Vaccines for Human and Veterinary Use

open access: yesViruses, 2022
The COVID-19 pandemic has highlighted the need for efficient vaccine platforms that can rapidly be developed and manufactured on a large scale to immunize the population against emerging viruses.
Julia P. C. Fulber, Amine A. Kamen
doaj   +1 more source

A Review on Rubella Vaccine: Iran (1975-2019) [PDF]

open access: yesArchives of Razi Institute, 2021
The first Attenuated rubella vaccine was developed by Parkman and Meyer in 1966. Ten years later in the 1975s, the rubella vaccine was developed in Razi Vaccine and serum research institute) RVSRI).
A Shafayi, A Mohammadi
doaj   +1 more source

Personalized Cancer Vaccines Go Viral: Viral Vectors in the Era of Personalized Immunotherapy of Cancer

open access: yesInternational Journal of Molecular Sciences, 2023
The aim of personalized cancer vaccines is to elicit potent and tumor-specific immune responses against neoantigens specific to each patient and to establish durable immunity, while minimizing the adverse events.
L. Seclì   +6 more
semanticscholar   +1 more source

Capripoxvirus antibodies detection: Relationship between the two methods alpha and beta of virus neutralisation test [PDF]

open access: yesOpen Veterinary Journal, 2018
Virus neutralisation test (VNT) of capripoxvirus (CaPVs) was studied to assess the post-vaccination (vaccine effectiveness) or post-infection antibodies level using two methods: alpha-VNT and beta-VNT which are generally carried out to measure the ...
Mohamed Hamidouche   +6 more
doaj   +1 more source

Highly pathogenic avian influenza A/Guangdong/17SF003/2016 is immunogenic and induces cross-protection against antigenically divergent H7N9 viruses

open access: yesnpj Vaccines, 2021
Avian influenza A(H7N9) epidemics have a fatality rate of approximately 40%. Previous studies reported that low pathogenic avian influenza (LPAI)-derived candidate vaccine viruses (CVVs) are poorly immunogenic.
Peter Radvak   +10 more
doaj   +1 more source

Mapping the Antibody Repertoires in Ferrets with Repeated Influenza A/H3 Infections: Is Original Antigenic Sin Really “Sinful”?

open access: yesViruses, 2023
The influenza-specific antibody repertoire is continuously reshaped by infection and vaccination. The host immune response to contemporary viruses can be redirected to preferentially boost antibodies specific for viruses encountered early in life, a ...
Tal Einav   +5 more
doaj   +1 more source

Vaccines against Major Poultry Viral Diseases: Strategies to Improve the Breadth and Protective Efficacy

open access: yesViruses, 2022
The poultry industry is the largest source of meat and eggs for human consumption worldwide. However, viral outbreaks in farmed stock are a common occurrence and a major source of concern for the industry.
Rajamanonmani Ravikumar   +2 more
semanticscholar   +1 more source

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