Results 41 to 50 of about 1,560,419 (396)
Recombinant viral vaccines for cancer [PDF]
Trends in Molecular Medicine, 2012 Cancer arises from 'self' in a series of steps that are all subject to immunoediting. Therefore, therapeutic cancer vaccines must stimulate an immune response against tumour antigens that have already evaded the body's immune defences. Vaccines presenting a tumour antigen in the context of obvious danger signals seem more likely to stimulate a response.
Cawood, R +6 more
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Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines
npj Vaccines, 2021 Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-recognition receptors. They function as sensors of invading pathogens through recognition of pathogen-associated molecular patterns.
Rossella Sartorius +4 more
semanticscholar +1 more source
Vaccines in the Prevention of Viral Pneumonia [PDF]
Clinics in Chest Medicine, 2017 Pneumonia is of great global public health importance. Viral infections play both direct and indirect parts in its cause across the globe. Influenza is a leading cause of viral pneumonia in both children and adults, and respiratory syncytial virus is increasingly recognized as causing disease at both extremes of age.
Fraser, CS, Jha, A, Openshaw, PJM
openaire +4 more sources
Translating viral vaccines into immunity
Science, 2021 How adenoviral vaccines orchestrate adaptive immunity from innate responses is ...
Juno, Jennifer A., OConnor, Shelby L.
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Review of COVID-19 viral vector-based vaccines and COVID-19 variants.
Le infezioni in medicina, 2021 The concept of viral vector-based vaccine was introduced in 1972 by Jackson et al and in 1982 Moss et al introduced the use of vaccinia virus as a transient gene expression vector.
Rachana Vanaparthy +3 more
semanticscholar +1 more source
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
, 2014 Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow +30 more
core +3 more sources
Combating Human Viral Diseases: Will Plant-Based Vaccines Be the Answer?
Vaccines, 2021 Molecular pharming or the technology of application of plants and plant cell culture to manufacture high-value recombinant proteins has progressed a long way over the last three decades.
S. Venkataraman +3 more
semanticscholar +1 more source
Influenza and memory T cells : how to awake the force [PDF]
, 2016 Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen +12 more
core +3 more sources
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8+ T Cell Responses, Enabling Faster Resolution of Influenza Disease [PDF]
, 2016 Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of
Bogen, B +8 more
core +7 more sources
Viral Vaccines in India: An Overview [PDF]
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 2012 Viruses cause a large number of diseases in humans, some of which are fatal, while others are highly debilitating. A majority of viral diseases attack infants and young children, while others strike people in their prime. Development of preventive measures against viral diseases is, therefore, of paramount importance.
Kaushik Bharati, Sudhanshu Vrati
openaire +3 more sources