Results 61 to 70 of about 349,023 (332)

Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study

Frontiers in Immunology, 2022
Current vaccination strategies against influenza focus on generating an antibody response against the viral haemagglutination surface protein, however there is increasing interest in neuraminidase (NA) as a target for vaccine development. A critical tool
Marie-Clotilde Bernard, Joanna Waldock, Sylvie Commandeur, Lea Strauß, Claudia Maria Trombetta, Serena Marchi, Fan Zhou, Serge van de Witte, Peter van Amsterdam, Sammy Ho, Katja Hoschler, Vladimir Lugovtsev, Jerry P. Weir, Emanuele Montomoli, Rebecca J. Cox, Othmar G. Engelhardt, Damien Friel, Ralf Wagner, Thierry Ollinger, Sophie Germain, Hanna Sediri-Schön   +20 more
doaj   +1 more source

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe, Bernard, Julie, Bernex, Florence, Castagné, Nathalie, Deplanche, Martine, Deville, Sébastien, Dubosclard, Virginie, Dubuquoy, Catherine, Durand, Guillaume, Eléouët, Jean-François, Meyer, Gilles, Petit-Camurdan, Agnès, Riffault, Sabine, Schwartz-Cornil, Isabelle, Soulestin, Marion   +14 more
core   +2 more sources

Outside in – inside out. Creating focus on the patient – a vaccine company perspective

Human Vaccines & Immunotherapeutics, 2018
Involving patients in the development of medicines and vaccines should result in benefits to patients. The vaccine recipient is usually a healthy person.
Denis Sohy, Isabelle Dusart, Philibert Goulet, Diane Visy, Luc Gasthuys, Tatjana Poplazarova, Thomas Breuer, Norman Begg   +7 more
doaj   +1 more source

The comparative value of feline virology research: can findings from the feline lentiviral vaccine be translated to humans? [PDF]

, 2017
Feline immunodeficiency virus (FIV) is a lentivirus of domestic cats that shares several similarities with its human counterpart, human immunodeficiency virus (HIV).
Beczkowski, Paweł M., Harris, Matthes, Hosie, Margaret J., Logan, Nicola, Techakriengkrai, Navapon, Willett, Brian   +5 more
core   +1 more source

Establishing a Robust Manufacturing Platform for Recombinant Veterinary Vaccines: An Adenovirus-Vector Vaccine to Control Newcastle Disease Virus Infections of Poultry in Sub-Saharan Africa

Vaccines, 2020
Developing vaccine technology platforms to respond to pandemic threats or zoonotic diseases is a worldwide high priority. The risk of infectious diseases transmitted from wildlife and domestic animals to humans makes veterinary vaccination and animal ...
Omar Farnós, Esayas Gelaye, Khaled Trabelsi, Alice Bernier, Kumar Subramani, Héla Kallel, Martha Yami, Amine A. Kamen   +7 more
doaj   +1 more source

SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Activity

Viruses, 2021
The SARS-CoV-2 B.1.617 lineage variants, Kappa (B.1.617.1) and Delta (B.1.617.2, AY) emerged during the second wave of infections in India, but the Delta variants have become dominant worldwide and continue to evolve.
Sabari Nath Neerukonda, Russell Vassell, Sabrina Lusvarghi, Richard Wang, Fernando Echegaray, Lisa Bentley, Ann E. Eakin, Karl J. Erlandson, Leah C. Katzelnick, Carol D. Weiss, Wei Wang   +10 more
doaj   +1 more source

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang, Fang-Hoover, June, Freed, Daniel C, Fu, Tong-Ming, Li, Fengsheng, Pereira, Lenore, Petitt, Matthew, Tabata, Takako, Wang, Dai   +8 more
core   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine

Viruses
The thermostability of vaccines, particularly enveloped viral vectored vaccines, remains a challenge to their delivery wherever needed. The freeze-drying of viral vectored vaccines is a promising approach but remains challenging due to the water removal ...
MD Faizul Hussain Khan, Maryam Youssef, Sean Nesdoly, Amine A. Kamen   +3 more
doaj   +1 more source

Determination of antibodies to Caprine arthritis encephalitis virus in goats and sheep in some localities in Sudan

Journal of Advanced Veterinary and Animal Research, 2016
Objective: Caprine arthritis encephalitis (CAE) infection is existing worldwide causing economic loss in goat production. This work was conducted to investigate the prevalence of CAE in local and foreign goat breeds and sheep in different localities in ...
Wegdan Hassan Ali, Intisar Kamil Saeed, Shaza Mohammed Mutwakil, Omer A. Algezoli, Abdelgader Ballal Mohammed, Ihsan Hussein Ahmed, Sahar Mohammed Elhassan, Baraa Abdelaziz Ahmed, Rayan M. A. Asil, Saafass M. A. Alsarraj, Abdelmhmoud Atalmanan Abdelgader and Yahia Hassan Ali   +10 more
doaj   +1 more source