Results 71 to 80 of about 1,560,419 (396)

The evolution of the mechanisms of SARS-CoV-2 evolution revealing vaccine-resistant mutations in Europe and America [PDF]

open access: yesarXiv, 2021
The importance of understanding SARS-CoV-2 evolution cannot be overemphasized. Recent studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 evolution, which favors mutations that strengthen viral infectivity. We demonstrate that vaccine-breakthrough or antibody-resistant mutations provide a new mechanism of viral evolution ...
arxiv  

The effect of diatomaceous earth in live, attenuated infectious bronchitis vaccine, immune responses, and protection against challenge. [PDF]

open access: yes, 2017
Live virus vaccines are commonly used in poultry production, particularly in broilers. Massive application and generation of a protective local mucosal and humoral immunity with no adverse effects is the main goal for this strategy.
Corbeil, Lynette B   +3 more
core   +1 more source

Semiparametric logistic regression for inference on relative vaccine efficacy in case-only studies with informative missingness [PDF]

open access: yesarXiv, 2023
We develop semiparametric methods for estimating subgroup-specific relative vaccine efficacy against multiple viral strains in a partially vaccinated population. Focusing on observational case-only studies, we address informative missingness in strain type due to vaccination status, pre-vaccination characteristics, and post-infection factors such as ...
arxiv  

Development and Applications of Viral Vectored Vaccines to Combat Zoonotic and Emerging Public Health Threats

open access: yesVaccines, 2020
Vaccination is arguably the most cost-effective preventative measure against infectious diseases. While vaccines have been successfully developed against certain viruses (e.g., yellow fever virus, polio virus, and human papilloma virus HPV), those ...
Sophia M. Vrba   +4 more
semanticscholar   +1 more source

Development of a novel equine influenza virus live-attenuated vaccine [PDF]

open access: yes, 2018
H3N8 equine influenza virus (EIV) is an important and significant respiratory pathogen of horses. EIV is enzootic in Europe and North America, mainly due to the suboptimal efficacy of current vaccines. We describe, for the first time, the generation of a
Chambers, Thomas M.   +5 more
core   +1 more source

The Immunological and Epidemiological Effectiveness of Pediatric Single-Dose Vaccination against Hepatitis A 9 to 11 Years after Its Implementation in the Tyva Republic, the Russian Federation

open access: yesVaccines
Since 2012, universal single-dose HAV vaccination in children aged 3 years and older has been implemented in the Tyva Republic, a region of the Russian Federation.
Maria A. Lopatukhina   +9 more
doaj   +1 more source

VACCINATIONS | Viral

open access: yes, 2006
Vaccines are preparations of weakened or killed viruses or viral subunits that trigger specific protective immunity. Vaccination is the single most effective tool for preventing communicable disease, highlighted by the achievements of the smallpox and poliomyelitis eradication programs and the rise in infections for which no effective vaccine is ...
Olszewska, W.   +2 more
openaire   +1 more source

Genome Analysis and Replication Studies of the African Green Monkey Simian Foamy Virus Serotype 3 Strain FV2014

open access: yesViruses, 2020
African green monkey (AGM) spumaretroviruses have been less well-studied than other simian foamy viruses (SFVs). We report the biological and genomic characterization of SFVcae_FV2014, which was the first foamy virus isolated from an African green monkey
Sandra M. Fuentes   +4 more
doaj   +1 more source

Vaccine-induced skewing of T cell responses protects against Chikungunya virus disease [PDF]

open access: yes, 2019
Chikungunya virus (CHIKV) infections can cause severe and debilitating joint and muscular pain that can be long lasting. Current CHIKV vaccines under development rely on the generation of neutralizing antibodies for protection; however, the role of T ...
Ando, Takeshi   +13 more
core   +3 more sources

Competing Heterogeneities in Vaccine Effectiveness Estimation [PDF]

open access: yes, 2023
Understanding waning of vaccine-induced protection is important for both immunology and public health. Population heterogeneities in underlying (pre-vaccination) susceptibility and vaccine response can cause measured vaccine effectiveness (mVE) to change over time even in the absence of pathogen evolution and any actual waning of immune responses.
arxiv   +1 more source

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