Results 211 to 220 of about 657,629 (304)

Adeno-associated viral vector resource for the RNA-targeting Cas13d: A comparison of high-fidelity variants, DjCas13d and hfCas13d. [PDF]

Mol Ther Methods Clin Dev
Back F, Sandoval A, Vu LM, Hong VM, Bhaskara A, Rodriguez SR, O'Brien JT, Kolber BJ, Kroener S, Ploski JE.   +9 more
europepmc   +1 more source

Viral Vector-Based Gene Therapy. [PDF]

Int J Mol Sci, 2023
Li X, Le Y, Zhang Z, Nian X, Liu B, Yang X.   +5 more
europepmc   +1 more source

987. Effects of Promoter and Viral Dose on AAV Vector-Mediated Gene Expression, Efficacy and Survival in a Mouse Model of Niemann-Pick A Disease [PDF]

, 2007

openalex   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

A breath of fresh air: targeted non-viral in vivo gene correction in the mammalian lung

Signal Transduction and Targeted Therapy
Jixin Liu, Dirk Grimm
doaj   +1 more source

Immunogenicity and Contraceptive Potential of a Classical Swine Fever Viral Vector Live Vaccine Strain Containing Pig Gonadotropin-Releasing Hormone. [PDF]

Vaccines (Basel)
An DJ, Shin JH, Choe S, Lee YH, Jang MK, An BH, Park GN, Cho YS, Chang KS.   +8 more
europepmc   +1 more source

86. AAV vs HDAd Viral Vectors as Promising Agents for the Biopump Therapeutic System [PDF]

, 2014

openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Towards enhancing photostability and adeno-associated viral vector delivery for genetically encoded plasma fluorescent labels. [PDF]

Neurophotonics
Knak PG, Vittani M, Lee AB, Nedergaard L, Elleholm NV, Wang X, Bojarowska Z, Martens MC, Konno A, Hirai H, Nedergaard M, Hirase H.   +11 more
europepmc   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source