Results 21 to 30 of about 657,629 (304)

Pan-European Chikungunya surveillance: Designing risk stratified surveillance zones [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Tilston et alThe first documented transmission of Chikungunya within Europe took place in Italy during the summer of 2007.
Skelly, C, Tilston, N, Weinstein, P
core   +4 more sources

Dual monoclonal antibody-based sandwich ELISA for detection of in vitro packaged Ebola virus

Diagnostic Pathology, 2018
Background Rapid transmission and high mortality of Ebola virus disease (EVD) highlight a urgent need of large scale, convenient and effective measure for Ebola virus screening. Application of monoclonal antibodies (mAbs) are crucial for establishment of
Junjie Zai, Kai Yi, Lilan Xie, Jiping Zhu, Xiaoting Feng, Yaoming Li   +5 more
doaj   +1 more source

Therapeutic modulation of gene expression in the disease state: Treatment strategies and approaches for the development of next-generation of the epigenetic drugs

Frontiers in Bioengineering and Biotechnology, 2022
Epigenetic dysregulation is an important determinant of many pathological conditions and diseases. Designer molecules that can specifically target endogenous DNA sequences provide a means to therapeutically modulate gene function.
Joseph Rittiner, Joseph Rittiner, Joseph Rittiner, Mohanapriya Cumaran, Mohanapriya Cumaran, Mohanapriya Cumaran, Sahil Malhotra, Sahil Malhotra, Sahil Malhotra, Boris Kantor, Boris Kantor, Boris Kantor   +11 more
doaj   +1 more source

Culex tarsalis is a competent vector species for Cache Valley virus [PDF]

, 2018
Background: Cache Valley virus (CVV) is a mosquito-borne orthobunyavirus endemic in North America. The virus is an important agricultural pathogen leading to abortion and embryonic lethality in ruminant species, especially sheep.
Alto, Barry W., Ayers, Victoria B., Blitvich, Bradley J., Dunlop, James I., Higgs, Stephen, Huang, Yan-Jang, Kohl, Alain, Lyons, Amy C., Park, So Lee, Unlu, Isik, Vanlandingham, Dana L.   +10 more
core   +1 more source

A comparison of commercial light-emitting diode baited suction traps for surveillance of Culicoides in northern Europe

Parasites & Vectors, 2015
Background The response of Culicoides biting midges (Diptera: Ceratopogonidae) to artificial light sources has led to the use of light-suction traps in surveillance programmes.
Andrew Hope, Simon Gubbins, Christopher Sanders, Eric Denison, James Barber, Francesca Stubbins, Matthew Baylis, Simon Carpenter   +7 more
doaj   +1 more source

Viral vector-based influenza vaccines [PDF]

, 2016
Antigenic drift of seasonal influenza viruses and the occasional introduction of influenza viruses of novel subtypes into the human population complicate the timely production of effective vaccines that antigenically match the virus strains that cause ...
Rimmelzwaan, G.F. (Guus), Vries, R.D. (Rory) de   +1 more
core   +3 more sources

Emerging and re-emerging zoonotic viral diseases in Southeast Asia: One Health challenge

Frontiers in Public Health, 2023
The ongoing significant social, environmental, and economic changes in Southeast Asia (SEA) make the region highly vulnerable to the emergence and re-emergence of zoonotic viral diseases.
Paola Mariela Saba Villarroel, Paola Mariela Saba Villarroel, Nuttamonpat Gumpangseth, Nuttamonpat Gumpangseth, Thanaphon Songhong, Thanaphon Songhong, Sakda Yainoy, Arnaud Monteil, Arnaud Monteil, Pornsawan Leaungwutiwong, Dorothée Missé, Sineewanlaya Wichit, Sineewanlaya Wichit   +12 more
doaj   +1 more source

Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy. [PDF]

, 2017
Gene therapy by engineering patient's own blood cells to confer HIV resistance can potentially lead to a functional cure for AIDS. Toward this goal, we have previously developed an anti-HIV lentivirus vector that deploys a combination of shRNA, ribozyme ...
Castanotto, Daniela, Li, Haitang, Pang, Ka Ming, Rossi, John J, Scherer, Lisa   +4 more
core   +1 more source

Transcriptional Profiling of STAT1 Gain-of-Function Reveals Common and Mutation-Specific Fingerprints

Frontiers in Immunology, 2021
STAT1 gain-of-function (GOF) is a primary immunodeficiency typically characterized by chronic mucocutaneous candidiasis (CMC), recurrent respiratory infections, and autoimmunity.
Simone Giovannozzi, Simone Giovannozzi, Jonas Demeulemeester, Jonas Demeulemeester, Rik Schrijvers, Rik Gijsbers, Rik Gijsbers   +6 more
doaj   +1 more source

Targeted surveillance reveals native and invasive mosquito species infected with Usutu virus

Parasites & Vectors, 2019
Background The emergence of Usutu virus (USUV) in Europe was first reported in Austria, 2001, and the virus has since spread to many European countries. Initial outbreaks are marked by a mass die-off of European blackbirds (Turdus merula) and other bird ...
Jeremy V. Camp, Jolanta Kolodziejek, Norbert Nowotny   +2 more
doaj   +1 more source