Results 361 to 370 of about 2,747,170 (398)

Viral vectors/Viral latency (II)/Antiretroviral therapeutics [PDF]

Journal of NeuroVirology, 2002
Features of the life cycle and genomic structure of HSV1 provide an ideal starting point for the engineering of: 1) tumorselective recombinant mutants, and 2) vectors for delivery of entire genomic loci into cells. For the rst application, we have engineered HSV mutants that target defects in the p16 tumor suppressor pathway, thereby allowing selective
H.-J. von Giesen, L. Cosby
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Viral Vector Production: Adenovirus

2016
Adenoviral vectors have proven to be valuable resources in the development of novel therapies aimed at targeting pathological conditions of the central nervous system, including Alzheimer's disease and neoplastic brain lesions. Not only can some genetically engineered adenoviral vectors achieve remarkably efficient and specific gene delivery to target ...
Ramin A. Morshed, Brenda Auffinger, Julius W. Kim, Maciej S. Lesniak, J. Robert Kane, Jian Qiao   +5 more
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Viral Vector-Based Transduction of Slice Cultures.

Cold Spring Harbor Protocols, 2017
Transgenes can be introduced into the cells of organotypic slice cultures using different delivery methods, such as biolistic transfection, electroporation, and viral vector-based transduction.
J. Simon Wiegert, C. Gee, T. Oertner
semanticscholar   +1 more source

Viral vectors as vaccine carriers

Current Opinion in Virology, 2016
This chapter reviews the performance of viral vectors based on adenoviruses or adeno-associated virus as vaccine carriers for infectious diseases. Replication-defective adenovirus vectors based on multiple human or non-human serotypes have consistently induced potent transgene product-specific B and T cell responses and are increasingly being explored ...
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Geminiviruses: plant viral vectors

Current Opinion in Genetics & Development, 1993
Geminiviruses are being used as convenient autonomously replicating vectors for foreign gene amplification in plants. Using tissue culture techniques, they have been adapted for the analysis of the regulation of gene expression in a wide range of hosts, including both mono- and dicotyledonous species.
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Progress of cationic gene delivery reagents for non-viral vector

Applied Microbiology and Biotechnology, 2021
Kai Ma, Chun-liu Mi, Xiang-xiang Cao, Tian-yun Wang   +3 more
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Immune Response to Viral Vectors

1998
Recombinant viral vectors are an important class of therapeutic gene delivery vehicles. However, because they expose the recipient to foreign proteins, the host immune response is an important consideration in their use in the treatment of human disease.
Jason G. Smith, Stephen L. Eck
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Vaccinia Viral Vectors [PDF]

, 2000
David L. Bartlett, J. Andrea McCart
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Viral Vector

Definitions, 2020

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Adeno-associated Viral Vectors

1995
Viral vectors, which are capable of infecting virtually every cell in a target population, are the most efficient method for delivering nucleic acids into mammalian cells. Viral expression vectors, reviewed by Rigby (1983) have been developed using DNA viruses, such as papova (i.e., SV40), adeno, herpes, and pox viruses and RNA viruses, such as ...
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