Results 51 to 60 of about 1,978,611 (289)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
, 2016 An Air Force colonel pilot faces an emergency on her refueling plane and saves the day. Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L.
Atwood, Marcy
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Virginia Library Leadership Academy 2014
Virginia Libraries, 2013 The Leadership Development Forum of the Virginia Library Association is sponsoring the 3rd Virginia Library Leadership Academy (VALLA), facilitated by nationally recognized speaker, Dr.
Teresa Doherty
doaj +1 more source
Chinese Journal of Magnetic Resonance, 2020 This paper proposes an image reconstruction method for simultaneous multi-slice imaging (SMS) by combining the virtual conjugate coil (VCC) technology and robust artificial-neural-networks for k-space interpolation (RAKI).
WANG Wan-ting +4 more
doaj +1 more source
A first insight into the genetics of maturity trait in Runner × Virginia types peanut background
Scientific Reports, 2022 'Runner' and 'Virginia', the two main market types of Arachis hypogaea subspecies hypogaea, differ in several agricultural and industrial characteristics. One such trait is time to maturation (TTM), contributing to the specific environmental adaptability
Srinivas Kunta +7 more
doaj +1 more source
Keep on Keeping On : African Americans and the Implementation of Brown v. Board of Education in Virginia [PDF]
, 2008 This chapter examines African American efforts to implement the Brown decision in Virginia. While considering how government officials, segregationist organizations, and white supporters influenced the implementation process, this study focuses on how ...
Daugherity, Brian J.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A Turning Point for Richmond: The Virginia Historical Society's Civil War Exhibition
Southern Spaces, 2011 William G. Thomas III reviews the Virginia Historial Society's exhibit, "An American Turning Point: The Civil War in Virginia."
William G. Thomas III
doaj +1 more source