Results 181 to 190 of about 104,970 (255)

Structural choreography of bacteriophage N4 ejection proteins and the giant virion-associated RNA polymerase. [PDF]

Nat Commun
Bellis NF, Lokareddy RK, Pavlenok M, Jacobs RQ, Cooper Horton SL, Kizziah JL, Forti F, Schneider DA, Niederweis M, Briani F, Cingolani G.   +10 more
europepmc   +1 more source

Triple Threat: Elucidating Evolution Under Antibiotic, Metal, and Phage Pressure in Escherichia coli

Ecology and Evolution, Volume 16, Issue 9, September 2026.
Antibiotic resistance threatens treatment of bacterial infections, increasing research into alternative therapies, in particular whether new resistances will arise to these novel treatments. We evolved bacteria under phage, antibiotic, and heavy metal exposure.
Lindsey W. McGee, Noah K. Radtke, Gretchen S. Taylor, Joseph L. Graves Jr., Liesl Jeffers‐Francis   +4 more
wiley   +1 more source

Structure of NO16, a marine non-tailed vibriophage with an unusual symmetry-mismatched vertex arrangement. [PDF]

PLoS Pathog
Otaegi-Ugartemendia S, Condezo GN, Martínez M, Kalatzis PG, Middelboe M, San Martín C.   +5 more
europepmc   +1 more source

The C‐Type Lectin Mincle Serves as a Pattern Recognition Receptor for the Lipid Envelope of Human Cytomegalovirus

European Journal of Immunology, Volume 56, Issue 9, September 2026.
Whether viral lipids can directly interact with pattern recognition receptors to modulate antiviral immune responses remains unclear. We show that Mincle‐dependent recognition of HCMV viral particles induces proinflammatory cytokine production in primary human macrophages.
Vladimir Bokun, Wengang Chai, Robert Buchanan, Elliot Murphy, Yan Liu, Beth Holder, Alexiane Decout   +6 more
wiley   +1 more source

Systematic mapping of insertion-tolerant regions enables capsid engineering of an infectious RNA phage. [PDF]

mBio
Choi S-Y, Kim M-J, Kwon OH, Park C, Bae H-W, Cho H, Cho Y-H.   +6 more
europepmc   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, Volume 3, Issue 3, September 2026.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Differential Hepatitis B Surface Antigen Glycan Isomer Kinetics Between Tenofovir Alafenamide and Entecavir: Hepatocellular Carcinoma Risk Stratification in Hepatitis B e Antigen-Positive Patients. [PDF]

J Viral Hepat
Kita Y, Murata A, Nago H, Yamaguchi M, Kato Y, Om R, Terai Y, Ikeda Y, Sato S, Sato S, Shimada Y, Genda T.   +11 more
europepmc   +1 more source

Predicting Oral HIV Pre‐Exposure Prophylaxis Efficacy in Cisgender Women Across Pregnancy and Postpartum

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Cisgender women face an increased risk of HIV acquisition during pregnancy and postpartum. Oral pre‐exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate (F/TDF) is recommended in pregnancy despite limited published pharmacokinetic (PK) and efficacy data during pregnancy.
Yifan Yu, Kristina M. Brooks, Gustavo F. Doncel, Brookie M. Best, Mark A. Marzinke, Mark Mirochnick, Peter L. Anderson, Landon Myer, Connie Celum, Renee Heffron, Jenell Coleman, Dvora L. Joseph Davey, Lanxin Zhang, Max von Kleist, Craig W. Hendrix, Jeremiah D. Momper, Robert Bies, Rachel K. Scott   +17 more
wiley   +1 more source

Cryo-ET of IgG bivalent binding on SARS-CoV-2 provides structural basis for antibody avidity. [PDF]

Nat Commun
Yao H, Song Y, Huang Q, Zhu M, Liang J, Zhang Z, Zhang X, Dong D, Shi D, Wu Z, Lu X, Wu H, Chen Y, Li S.   +13 more
europepmc   +1 more source

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng, Xiaowei Nan, Ting Wang, Junyao Xiong, Shuo Zhu, Chengjie Yang, Bibo Zhu, Youhui Si, Shengbo Cao, Jing Ye   +9 more
wiley   +1 more source