Results 121 to 130 of about 3,105,782 (329)

The influence of rivers on seabird foraging ecology

Biological Reviews, EarlyView.
ABSTRACT Rivers act as vital arteries to the world's oceans, delivering fresh water and nutrients that sustain marine ecosystems. Globally, river flow increasingly is being altered by climate change and anthropogenic pressures; yet the significance of rivers to predatory marine species, such as seabirds, and the extent to which river‐related changes ...
Julia B. Morais, Andre Chiaradia, Richard D. Reina   +2 more
wiley   +1 more source

Predictors of virological failure in HIV‐1‐infected patients switching to dolutegravir maintenance monotherapy

HIV Medicine, 2018
The Dolutegravir Monotherapy for HIV (DOMONO; NCT02401828) study showed that maintenance monotherapy with dolutegravir (DTG) is associated with virological failure (VF) and leads to DTG resistance and as a result should not be used.
I. Wijting, S. Rutsaert, C. Rokx, D. Burger, A. Verbon, J. V. Kampen, C. Boucher, B. Rijnders, L. Vandekerckhove   +8 more
semanticscholar   +1 more source

The role of drug resistance in poor viral suppression in rural South Africa: findings from a population-based study. [PDF]

, 2020
BACKGROUND:Understanding factors driving virological failure, including the contribution of HIV drug resistance mutations (DRM), is critical to ensuring HIV treatment remains effective.
Barnhart, Scott, Gilmore, Hailey J, Grignon, Jessica S, Hunt, Gillian, Liegler, Teri, Lippman, Sheri A, Mooney, Alyssa C, Prach, Lisa M, Puren, Adrian, Truong, Hong-Ha M   +9 more
core  

Treatment of Young Children with HIV Infection: Using Evidence to Inform Policymakers [PDF]

, 2012
PMCID: PMC3404108This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Abrams, EJ, Cotton, M, Gibb, DM, Mulenga, V, Musoke, P, Penazzato, M, Prendergast, AJ   +6 more
core   +3 more sources

Extent, characteristics and policy applications of Key Biodiversity Areas

Biological Reviews, EarlyView.
ABSTRACT A global standard for the identification of Key Biodiversity Areas (KBAs) was published 10 years ago to provide a unified set of criteria for identifying ‘sites of significance for the global persistence of biodiversity’. We review the initiative's origins, the KBA identification process, characteristics of the current network, threats, policy
Stuart H. M. Butchart, Olivia Crowe, Tom Scott, Andrew J. Plumptre, Megan Eldred, Ellen McKee, Zoltan Waliczky, Ibrahim Al Hasani, Adrián B. Azpiroz, Daniele Baisero, Fred Barasa, Alison E. Beresford, Bezeng S. Bezeng, Charlotte Boyd, Thomas M. Brooks, Graeme Buchanan, Gill Bunting, Sofia Capellan, Neil Cox, Tim R. B. Davenport, Tammy E. Davies, Gina Della Togna, Wendy Elliott, Matt Foster, Jo Gilbert, Jonathan M. Handley, Diego Juffe‐Bignoli, Victoria R. Jones, Naomi Kingston, Jeannot Kivono, John Lamoreux, Penny F. Langhammer, James Lewis, Bruce Liggitt, Daniel Marnewick, Paul Matiku, Erin McCreless, Rachel A. Neugarten, Catherine Numa, Mark O'Brien, Madhu Rao, Ciara Raudsepp‐Hearne, Justina C. Ray, Samridhi Rijal, Jon Paul Rodríguez, Jurgis Sapijanskas, Wes Sechrest, Martin Sneary, Andrew Snyder, Konstantina Spiliopoulou, Thomas Starnes, Cecilia Tobar, Gautam Surya, Marcelo F. Tognelli, Andrew W. Tordoff, Maria G. Toscano, Yongyut Trisurat, Amy Upgren   +57 more
wiley   +1 more source

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

EBioMedicine, 2017
Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen.
Soo-Yon Rhee, V. Varghese, S. Holmes, G. V. Van Zyl, K. Steegen, M. Boyd, D. Cooper, S. Nsanzimana, S. Saravanan, C. Charpentier, Túlio de Oliveira, Mary-Ann Etiebet, Federico García, D. Goedhals, P. Gómes, H. Günthard, R. Hamers, C. Hoffmann, G. Hunt, A. Jiamsakul, P. Kaleebu, P. Kanki, R. Kantor, B. Kerschberger, V. Marconi, Jean d’Amour Ndahimana, N. Ndembi, N. Ngo-Giang-Huong, C. Rokx, M. Santoro, J. Schapiro, Daniel Schmidt, L. Seu, K. Sigaloff, S. Sirivichayakul, Lindiwe Skhosana, H. Sunpath, Michele W. Tang, Chunfu Yang, S. Carmona, Ravindra K. Gupta, R. Shafer   +41 more
semanticscholar   +1 more source

Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring. [PDF]

, 2009
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from
Boulle, A, Braitstein, P, Brinkhof, Martin, Calmy, A, Dabis, F, Egger, Matthias, Jahn, A, Keiser, O, Keiser, Olivia, Kumarasamy, N, Lüthy, R, MacPhail, P, Nash, D, Pujades-Rodriguez, M, Schechter, M, Sprinz, E, Tuboi, S, Tweya, H, Wood, R   +18 more
core   +4 more sources

Diet of bird‐like troodontid dinosaurs: synthesis of a contentious clade

Biological Reviews, EarlyView.
ABSTRACT Troodontidae is a clade of small‐to medium‐sized maniraptoran theropods that mainly lived in Laurasia (modern Asia, North America and Europe) during the Jurassic and Cretaceous periods and are believed to have had a variety of diets. The uniqueness of troodontid teeth suggests that they diverged from the typical flesh‐based diet of non‐avian ...
Yui Chi Fan, Case Vincent Miller, Michael Pittman   +2 more
wiley   +1 more source

Virological and Immunological Antiretroviral Treatment Failure and Predictors Among HIV Positive Adult and Adolescent Clients in Southeast Ethiopia

HIV/AIDS: Research and Palliative Care, 2022
Ayele Mamo,1 Tesfaye Assefa,2 Wegene Negash,2 Yohannes Takelign,3 Biniyam Sahiledinigl,3 Zinash Teferu,3 Mesud Mohammed,1 Damtew Solomon,4 Habtamu Gezahegn,4 Kebebe Bekele,5 Demsu Zenbaba,3 Alelign Tasew,3 Anwar Tahir,2 Fikereab Desta,3 Tadele Regassa,4 ...
Mamo A, Assefa T, Negash W, Takelign Y, Sahiledinigl B, Teferu Z, Mohammed M, Solomon D, Gezahegn H, Bekele K, Zenbaba D, Tasew A, Tahir A, Desta F, Regassa T, Takele A, Regassa Z, Atilaw D   +17 more
doaj  

High levels of virological failure with major genotypic resistance mutations in HIV-1-infected children after 5 years of care according to WHO-recommended 1st-line and 2nd-line antiretroviral regimens in the Central African Republic

Medicine, 2017
A large cohort of 220 HIV-1-infected children (median [range] age: 12 [4–17] years) was cared and followed up in the Central African Republic, including 198 in 1st-line and 22 in 2nd-line antiretroviral regimens.
C. Mossoro-Kpinde, J. Gody, Ralph-Sydney Mboumba Bouassa, Olivia B. Mbitikon, Mohammad-Ali Jenabian, L. Robin, M. Matta, Kamal Zeitouni, J. D. D. Longo, C. Costiniuk, G. Grésenguet, N. C. Toure Kane, L. Bélec   +12 more
semanticscholar   +1 more source