Results 131 to 140 of about 1,735,150 (286)

Benefit of viral load testing for confirmation of immunological failure in HIV patients treated in rural Malawi. [PDF]

, 2011
Objective  Viral load testing is used in the HIV programme of Chiradzulu, Malawi, to confirm the diagnosis of immunological failure to prevent unnecessary switching to second-line therapy.
Robert Mogha, Mar Pujades-Rodríguez, McGuire, Megan, Rupa Kanapathipillai, Pujades-Rodriguez, Mar, Megan McGuire, Annette Heinzelmann, Heinzelmann, Annette, Kanapathipillai, Rupa, Mogha, Robert, Szumilin, Elisabeth, Elisabeth Szumilin   +11 more
core   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

HIV-1 genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan

, 2018
Hung-Chin Tsai,1–3 I-Tzu Chen,1 Susan Shin-Jung Lee,1,2 Yao-Shen Chen1,2 1Division of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 2Faculty of Medicine, School of Medicine, National Yang-Ming ...
Chen IT, Chen YS, Lee SS, Tsai HC
core  

FlowCytoMonitoR: An R‐Shiny Program for Advanced Monitoring Flow Cytometer Performance

Cytometry Part A, EarlyView.
ABSTRACT Flow cytometers are highly sensitive scientific instruments that need to be in optimal condition to provide accurate and reliable data. To ensure consistent performance, cytometer performance is regularly assessed by measuring standardized reference particles during a quality control (QC) measurement.
Britt Kolen, G. IJsbrand Reyneveld, Tom B. Kuipers, Marjolijn Hameetman, Hailiang Mei, Tamar Tak   +5 more
wiley   +1 more source

Association between PDR and virological failure (metanalysis).

Association between PDR and virological failure (metanalysis).
Ebako Ndip Takem (18389518), Clement Ndongmo (16447112), Christopher Coox (18389521), Emily Kainne Dokubo (3694843), Judith Shang (16447115)   +4 more
core   +1 more source

Velociraptor Machine Learning Quantifies Similarity to Known Cell Types and Matches Cells Across Flow and Imaging Cytometry Platforms

Cytometry Part A, EarlyView.
ABSTRACT Suspension flow cytometry enables high‐throughput cellular profiling at the single cell level, but these data lack positional information. Conversely, tissue‐based imaging cytometry techniques reveal a cell's location within the tissue architecture and can provide insight into cell biology.
Claire E. Cross, Asa A. Brockman, Rebecca A. Ihrie, Jonathan M. Irish   +3 more
wiley   +1 more source

Predictors of virological treatment failure among adult HIV patients on first-line antiretroviral therapy in Woldia and Dessie hospitals, Northeast Ethiopia: a case-control study

BMC Infectious Diseases, 2019
Background Virological treatment failure is a problem that a Human Immune Virus patient faces after starting treatment due to different factors. However, there were few studies done on the predictors of virological treatment failure among adult patients ...
Mohammed Ahmed, Hailu Merga, Habtemu Jarso   +2 more
doaj   +1 more source

Single‐Cell Reporter Dynamics During the First Two Rounds of Rhinovirus Plaque Growth

Cytometry Part A, EarlyView.
ABSTRACT When infection spreads from an initially infected cell through a cell monolayer, the resulting plaque records successive rounds of virus–cell interaction. Fluorescent reporter viruses permit this process to be followed at single‐cell resolution, but whether secondary infected cells retain detectable signatures associated with their plaque of ...
Rahul Ramachandran, Huicheng Shi, John Yin   +2 more
wiley   +1 more source

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

Health Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha, Moubani Dutta, Agnihiya Bosu   +2 more
wiley   +1 more source

Reduced-frequency bictegravir, emtricitabine, and tenofovir alafenamide in virologically suppressed adults with HIV: a single-centre randomised phase 2 pilot trial in Spain

EClinicalMedicine
Summary: Background: Reduced-frequency oral antiretroviral therapy may lessen treatment burden, but the exposure thresholds required to maintain virological suppression and the role of the HIV reservoir remain undefined. Methods: BETAF-RED was a 48-week,
Iván Chivite, Elisa Moraga, Abiu Sempere, Sònia Vicens-Artés, Pilar Callau, Cristina Rovira, Carmen Hurtado, Amedeo De Nicoló, Alejandro Sánchez-Molina, Berta Torres, Jordi Blanch, José Alcamí, José Luis Blanco, Antonio D’Avolio, Sonsoles Sánchez-Palomino, Elisa De Lazzari, Esteban Martínez   +16 more
doaj   +1 more source